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Related to peptidase: signal peptidase


 (pĕp′tĭ-dās′, -dāz′)


(ˈpɛptɪˌdeɪs; -ˌdeɪz)
(Biochemistry) any of a group of proteolytic enzymes that hydrolyse peptides to amino acids


(ˈpɛp tɪˌdeɪs, -ˌdeɪz)

any of the class of enzymes that catalyze the hydrolysis of peptides or peptones to amino acids.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.peptidase - any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis
caspase - any of a group of proteases that mediate apoptosis
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
angiotensin converting enzyme, angiotensin-converting enzyme, ACE - proteolytic enzyme that converts angiotensin I into angiotensin II
plasminogen activator, urokinase - protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis
renin - a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure
References in periodicals archive ?
Limited Tenders are invited for Procurement Of Collagen Peptidase
However, the available data on the inhibition of dipeptidyl peptidase in RA suggest that we should be careful in terms of the use of DPP-4 inhibitors in the treatment of diabetic patients with RA.
Samples were also taken for determination of peptide nitrogen (N), AA N, proteinase, peptidase, and deaminase, and isolation of DNA or RNA.
Introduced with a companion product called Dairylytic, Glutalytic "goes beyond the traditional DPPIV (dipeptidyl peptidase IV) enzyme.
Inhibition of dipeptidyl peptidase IV (DPP-IV) is one of the mechanisms explaining the hypoglycemic effect of berberine.
Leucine amino peptidase is one of the enzymes responsible for the hydrolysis of the proteins; they are present on the brush-border membrane of the mature enterocytes [17].
These nine articles describe some of the work being done to differentiate markers and use their presence to detect and treat a range of cancers, addressing the characterization of breast cancer subtypes in a large retrospective study, intraocular lymphoma markers, polymorphisms in genes associated with certain T-cell lymphomas, tumor antigens that are markers of minimal residual disease in acute myeloid leukemia, thyroid tumor markers, activity and expression of dipeptidyl peptidase IV and cathepsin H in human cutaneous melanoma compared to other common cancers, melanoma inhibitory activity as a serological marker in metastic melanoma, and the promise (or myth) of the tumor necrosis factor alpha receptors p55 and p75 in ovarian cancer detection.
Both compounds inhibit an enzyme called dipeptidyl peptidase 4 (DPP-4), which usually controls the body's production of a hormone, called GLP1.
Tokyo, Japan, June 15, 2006 - (JCN) - Ono Pharmaceutical and Banyu Pharmaceutical have obtained positive results in the recent clinical trials of sitagliptin, a dipeptidyl peptidase IV (DPP4) inhibitor.
OSI) Prosidion's lead compound, PSN9301, is a Dipeptidyl Peptidase IV (DPIV) inhibitor currently in Phase II clinical trials.
The rights to the dipeptidyl peptidase IV inhibitors had earlier been shared between PPD and Syrrx Inc.