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 (pĕr′ə-no͝or′ē-əm, -nyo͝or′-)
n. pl. per·i·neu·ri·a (-no͝or′ē-ə, -nyo͝or′-)
The sheath of connective tissue enclosing a bundle of nerve fibers.

[New Latin : peri- + Greek neuron, nerve; see neuron.]

per′i·neu′ri·al adj.


n, pl -neuria (-ˈnjʊərɪə)
(Anatomy) the connective tissue forming a sheath around a single bundle of nerve fibres
[C19: from New Latin, from peri- + Greek neuron nerve]
ˌperiˈneurial adj


(ˌpɛr əˈnʊər i əm, -ˈnyʊər-)

n., pl. -neu•ri•a (-ˈnʊər i ə, -ˈnyʊər-)
the sheath of connective tissue that encloses a bundle of peripheral nerve fibers.
[1835–45; < New Latin; see peri-, neur-, -ium2]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.perineurium - the sheath of connective tissue that covers a bundle of nerve fibers
connective tissue - tissue of mesodermal origin consisting of e.g. collagen fibroblasts and fatty cells; supports organs and fills spaces between them and forms tendons and ligaments
References in periodicals archive ?
With axonotmesis, the Schwann cell, the epineurium, and perineurium remain intact.
3) The individual axons of the nerve are surrounded by the endoneurium and subsequently bound together in fascicles by the perineurium.
The large peripheral nerves are composed of Schwann cell-axon complexes, supported and protected by 3 connective-tissue sheaths: endoneurium, perineurium, and epineurium.
Common to all head and neck tumours including skin cancers, nerve sheath spread via the endoneurium, perineurium or perineural lymphatics requires meticulous attention to the paths of the Vth and VIIth nerves and their branches.
Permeability of intraneural microvessels and perineurium following acute, graded experimental nerve compression.
Glut-1 is generally not detectable in benign or normal human tissue with the exceptions of erythrocytes, testicular germinal cells, renal tubules, perineurium of peripheral nerve, endothelial cells of blood-brain-barrier and placental trophoblasts (15).
Fascicular perineurium thickness, size, and position affect model predictions of neural excitation.
Benign intrapancreatic ducts are only rarely encountered in the vicinity of a nerve and almost never show invasion of the perineurium.
16) Silver can also be found intracellularly in endothelial cells of small blood vessels, mast cells, fibroblasts, and in the perineurium of peripheral nerves.
The neuroma is composed of a partially encapsulated aggregation or proliferation of nerves, often with thickened perineurium, intertwined with one another in a plexiform pattern.
Perineurial repair involves repairing the individual fascicles and placing sutures through the perineurium.