pernicious anemia


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Related to pernicious anemia: iron deficiency anemia, aplastic anemia

pernicious anemia

n.
A severe anemia most often affecting older adults, caused by failure of the stomach to absorb vitamin B12 and marked by a decrease in number and an increase in the size of red blood cells, by gastrointestinal disturbances, and by lesions of the spinal cord.

perni′cious ane′mia


n.
a severe anemia associated with inadequate intake or absorption of vitamin B12, characterized by defective production of red blood cells.
[1870–75]

pernicious anemia

Anemia is the lack of hemoglobin (oxygen- carrying part of blood). Pernicious anemia is due to a lack of vitamin B12, and is often caused by an autoimmune disorder.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.pernicious anemia - a chronic progressive anemia of older adults; thought to result from a lack of intrinsic factor (a substance secreted by the stomach that is responsible for the absorption of vitamin B12)
megaloblastic anaemia, megaloblastic anemia - anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia
metaplastic anaemia, metaplastic anemia - pernicious anemia in which the various formed elements in the blood are changed
anemia, anaemia - a deficiency of red blood cells
References in periodicals archive ?
Since patients with pernicious anemia had a characteristic lack of hydrochloric acid in their gastric juice, Castle suggested, in 1929, that it was some component of normal gastric juice that brought about the absorption of the antipernicious-anemia vitamin.
The progression of chronic atrophic gastritis to pernicious anemia may occur over time and may take 20 to 30 years before this may happen.
12] deficiency was related to pernicious anemia, gastrointestinal surgery, atrophic gastritis, poor protein intake, or medications.
We wouldn't want their pernicious anemia to go undisclosed because their deficiency lab test was masked by folate.
Minot and Murphy had demonstrated that there was a dietary factor in liver that reversed the onslaught of pernicious anemia (see 1926).
Conquest of pernicious anemia was completed with the discovery of vitamin B-12, the substance in liver extracts responsible for earlier cures.
I had chronic hypoglycemia, pernicious anemia, and sun sensitivity.
12] deficiency (including pernicious anemia and deficiency from gastric bypass surgery), empiric treatment is a reasonable alternative as long as serum [B.