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pernicious anemia

   Also found in: Medical, Legal, Encyclopedia, Wikipedia, Hutchinson 0.03 sec.
pernicious anemia
n.
A severe anemia most often affecting older adults, caused by failure of the stomach to absorb vitamin B12 and characterized by abnormally large red blood cells, gastrointestinal disturbances, and lesions of the spinal cord.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.pernicious anemia - a chronic progressive anemia of older adults; thought to result from a lack of intrinsic factor (a substance secreted by the stomach that is responsible for the absorption of vitamin B12)
megaloblastic anaemia, megaloblastic anemia - anemia characterized by many large immature and dysfunctional red blood cells (megaloblasts) in the bone marrow; associated with pernicious anemia
metaplastic anaemia, metaplastic anemia - pernicious anemia in which the various formed elements in the blood are changed
anemia, anaemia - a deficiency of red blood cells


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