Subsequent chapters address the identification of novel myeloid cell surface receptors, identifying novel ligands, phagocytosis
, genetic manipulation, macrophage activation, lipid signaling, and the secretion of matrix metalloproteinases by macrophages.
Since wear debris produced by orthopedic devices cannot be phagocytosed in this way, the process of phagocytosis
Interpretation & conclusions: When the infected HeLa cells were incubated with adherent macrophages, efficient phagocytosis
occurred and the release of virus into the culture medium was inhibited.
Hemophagocytic syndrome or hemophagocytic lymphohistiocytosis (HLH) is a clinical condition characterized by infiltration of the bone marrow and reticuloendothelial system by macrophages and activated histiocytes, leading to uncontrolled phagocytosis
of platelets, erythrocytes, lymphocytes and precursor cells.
The impairment of phagocytosis
leads to severe infections, as can be seen in patients with primary and secondary immunodeficiencies (1-6).
The term emperipolesis is synonymous with lymphocytophagocytosis, which differs from phagocytosis
in that the lymphocytes taken up by the cytoplasm are not attacked by enzymes and appear intact within the histiocytes.
The benefits of fever include the inhibition of replication of certain temperature-sensitive microbes, the stimulation of white blood cells to destroy microbes, the increase in metabolism of certain cells, the increase in phagocytosis
, the reduction in iron available for replication of bacteria, and the enhancement of the effects of interferon.
Sigush-Klinger-Holtz-Suss "In vitro phagocytosis
by crevicular phagocytes In many forms of periodontitis" J.
There are several possible explanations for this negative effect of antioxidants on mortality, one of which is that by eliminating (or reducing) free radicals we are interfering with some of the body's essential defence mechanisms such as apoptosis, phagocytosis
and detoxification which depend on reactive oxygen species.
The pathophysiology of vascular damage in maternal decidual vasculopathy is unknown, but the 2 key findings in the involved vessels in this lesion are well described: (1) atherosis appears to be histiocytic phagocytosis
of damaged endothelial cells of the spiral arteries, and (2) the dense pink fibrinoid necrosis may be some amalgam of the coagulation cascade proteins and intermediate filaments.
Outcomes were measured using polymorphnuclear cell migration, mononuclear cell percentages, degenerate leucocyte proportions and phagocytosis
Many instances of phagocytosis
were found in sponges fixed 2 h after feeding, but no beads or bacteria were found in sponges fixed 6 h after feeding.