MAOIs: Tranylcypromine and phenelzine
have been involved in oral abuse due to their amphetamine-like structure; series of cases have been reported in particular with tranylcypromine.
The rapid titration schedules present in certain package inserts (eg, phenelzine
(23)) should not be followed.
To date, the most common acrolein scavengers have been the FDA--[Food and Drug Administration] approved compounds containing a hydrazine group, such as hydralazine and phenelzine
," Shi says.
Medications used for depression include phenelzine
(Nardil), tranylcypromine (Parnate), and others.
Figure 2: The pharmacological agents that were tested included the following: First-generation antipsychotics: Flupenthixol decanoate Haloperidol Thiothixene Second-generation antipsychotics: Aripriprazole Olanzapine Ziprasidone Mood stabilisers: Carbamazepine Valproate semisodium Lamotrigine Topiramate Antidepressants: Amitriptyline Fluoxetine Fluvoxamine Phenelzine
sulfate Mianserin Dietary supplementation: Omega-3 fatty acid
To give only a mere example, it can be mentioned that phenelzine
, a well-recognized MAO inhibitor used as an antidepressant drug, also inhibits SSAO/VAP-1 [8, 9] and possesses neuroprotective properties [10, 11].
mitochondrial functional preservation and neuroprotection after traumatic brain injury related to scavenging of the lipid peroxidation-derived aldehyde 4-hydroxy-2-nonenal.
yogurt, sour cream, beef or chicken liver, salami, Names: phenelzine
, pepperoni, avocados, bananas, tranylcypromine canned figs, dried fruits (raisins, prunes), raspberries, sauerkraut, soy beans, soy sauce, fava beans, and chocolate.
These include warfarin (Coumadin) and antidepressants, such as phenelzine
2) Monamine Oxidase Inhibitors (MAOIs): They were also the first medications used to treat "Reactive Depression" and include Phenelzine
(Nardil), Selegiline (Emsam) and Tranylcypromine (Parnate).
and tranylcypromine are irreversible inhibitors of the monoamine oxidase enzyme (MAO).
The RANZCAP guidelines also recommend the use of phenelzine
or CBT for depression with atypical features.