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Related to phenoxybenzamine: prazosin


A long-acting alpha-blocker, C18H22ClNO, used in its hydrochloride form to treat high blood pressure, excessive sweating, and tachycardia caused by pheochromocytoma.
References in periodicals archive ?
Volume expansion therapy with phenoxybenzamine and hydroxyethyl starch 130/0.
After admission, heart rate (HR), BP, and ICP were controlled by esmolol, urapidil, phenoxybenzamine and mannitol.
After phenoxybenzamine blockade supplemented by metyrosine, the patient underwent robot-assisted laparoscopic partial right adrenalectomy.
17] The second phase is due to an active stimulation of the sympathetic system because its effects on the heart and peripheral vessels can be abolished with the addition of propranolol and phenoxybenzamine, respectively.
previous antihypertensive medications were stopped and the patient was started on oral phenoxybenzamine 10 mg twice daily, which was gradually titrated to 10 mg thrice daily, 20 mg thrice daily then to 20 mg four times daily to attain target blood pressure of 120/80 mmHg in supine position.
Therefore, the alpha-blocker phenoxybenzamine was modified and the beta-blocker was suspended.
Phenoxybenzamine therapy was initiated along with continuing metroprolol for blood pressure and rate control.
It is most commonly treated with [alpha]-adrenergic receptor blockers such as phenoxybenzamine or tamsulosin; 5[alpha]-reductase inhibitors such as finasteride; and male hormone inhibitors such as cyproterone or medroxyprogesterone; but also with TCM based phytopharmaceuticals such as Qianlie Kang Pule'an Tablets (QKPT) (Huang 2001).
On the basis these findings, the size of the mass, and the lack of interfering medications, the patient underwent [alpha]-blockade with 10 mg phenoxybenzamine 3 times per day and surgical resection of the adrenal mass.
35) Medications, including tricyclic antidepressants, decongestants, amphetamines, reserpine, and phenoxybenzamine, can cause false-positive results.
The contract has been signed to distribute and supply WellSpring Pharmaceutical's phenoxybenzamine hydrochloride capsules, USP of 10mg dose under the Prasco label in the United States.
The patient underwent preoperative preparation via blood volume expansion and a-blockade with phenoxybenzamine.