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phosphorylate

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
phos·pho·ryl·ate  (fsfr--lt)
tr.v. phos·pho·ryl·at·ed, phos·pho·ryl·at·ing, phos·pho·ryl·ates
To add a phosphate group to (an organic molecule).

phospho·ryl·ation n.
phospho·ryl·ative adj.


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The presence of alkalizing agents in the medium surrounding the mitochondrion breaks the electrostatic bonds between HK II and the mitochondrion, disrupting the immediate receipt of ATP and the ability of HK II to phosphorylate glucose (an absolute requirement for glucose transport) Cancerous cells have an absolute dependency upon the ATP generated by the glycolytic pathway within the mitochondrion for their energy requirement.
Mammalian polynucleotide kinase (PNK)3/phosphatase is a bifunctional enzyme that can phosphorylate 5'-OH termini and dephosphorylate 3'-phosphate termini of DNA (6, 7).
ROCK is an enzyme that phosphorylates cytoskeletal regulatory proteins and plays a role in cytoskeletal regulation.
 
 
 
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