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phosphorylation

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phos·pho·ryl·ate  (fsfr--lt)
tr.v. phos·pho·ryl·at·ed, phos·pho·ryl·at·ing, phos·pho·ryl·ates
To add a phosphate group to (an organic molecule).

phospho·ryl·ation n.
phospho·ryl·ative adj.

phosphorylation [ˌfɒsfərɪˈleɪʃən]
n
(Chemistry) the chemical or enzymic introduction into a compound of a phosphoryl group (a trivalent radical of phosphorus and oxygen)

phosphorylation  (fsfr--lshn)
The addition of a phosphate group to an organic molecule. Phosphorylation is important for many processes in living cells. ATP is formed during cell respiration from ADP by phosphorylation, as in the mitochondria of eukaryotic cells (oxidative phosphorylation) and the chloroplasts of plant cells (photosynthetic phosphorylation). Phosphorylation also regulates the activity of proteins, such as enzymes, which are often activated by the addition of a phosphate group and deactivated by its removal (called dephosphorylation).


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Hauxi Xu, from Burnham Institute, and colleagues showed that the RPS23R1 protein, which is encoded by the gene, triggers a signaling pathway within brain cells that inhibits a protein called GSK-3 (glycogen synthase kinase-3), which regulates both amyloid beta generation and tau phosphorylation.
00 Hardcover Methods in molecular biology; 527 QP552 The study of protein phosphorylation can provide key insights into the signal transduction pathways that are activated in cells in response to different stimuli, such as growth factor stimulation and exposure to toxicants.
Correspondingly, collagen-stimulated tyrosine phosphorylation of total platelet proteins was inhibited.
 
 
 
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