piperidine


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Related to piperidine: piperidine alkaloids

pi·per·i·dine

 (pī-pĕr′ĭ-dēn′, pĭ-)
n.
A strongly basic, colorless liquid heterocyclic amine, C5H11N, used in the manufacture of rubber and as a curing agent in epoxy resins.

piperidine

(pɪˈpɛrɪˌdiːn; -dɪn)
n
(Elements & Compounds) a colourless liquid heterocyclic compound with a peppery ammoniacal odour: used in making rubbers and curing epoxy resins. Formula: C5H11N

pi•per•i•dine

(pɪˈpɛr ɪˌdin, -dɪn, paɪ-, ˈpɪp ər ɪ-)

n.
a colorless, water-soluble liquid, C5H11N, used chiefly as a solvent.
[1850–55; < Latin piper pepper + -idine]
References in periodicals archive ?
NAMZARIC is contraindicated in patients with known hypersensitivity to memantine hydrochloride, donepezil hydrochloride, piperidine derivatives, or to any excipients used in the formulation.
CCG and the Hong Kong office of the DEA have collaborated since 2008 on Operation Zircon Pacific to monitor suspicious shipments through Hong Kong of acetic anhydride, acetyl chloride, piperidine, and potassium permanganate.
Eisai's Aricept (donepezil hydrochloride) is a piperidine derivative that acts centrally as a reversible AChEI.
The Pipe and Kim research groups devised a way to strongly link long polymer chains of a plastic called polyacrylic acid (PAA) with short strands of another called polyacryloyl piperidine (PAP).
Piperine, a piperidine alkaloid from Piper nigrum re-sensitizes P-gp, MRP1 and BCRP dependent multidrug resistant cancer cells.
4-t-butyl cyclohexanone, piperidine, paraformaldehyde, acetic acid, hydroxyl amine hydrochloride, sodium acetate, sodium bisulfite, potassium cyanide, diethyl ether and other chemicals were purchased from Merck chemical Co.
A piperidine amide extracted from Piper longum L fruit shows activity against Aedes aegypti mosquito larvae.
In the first experiments, the team exposed the pathogen's threadlike growth form, called "mycelium," to various piperideine or piperidine concentrations and monitored the effect on the colony size of P.
33] and Rossiter [34] Donepezil Name (Aricept) Derivative Piperidine Therapeutic class Acetylcholinesterase inhibitors Therapeutic dose 5-10 mg at night Starting dose 5 mg at night Presentation 5 mg, 10 mg tablets Interval between dose 4 weeks increases Common adverse effects Nausea, vomiting, (often transient) diarrhoea, fatigue, insomnia, muscle cramps, anorexia, headache, vivid dreams Half-life (h) 70 Metabolism CYP 2D6 CYP 3A4 Drug-drug interactions Yes Rivastigmine Name (Exelon) Derivative Carbamate Therapeutic class Acetylcholinesterase inhibitors Therapeutic dose 3-6 mg 2 x daily Starting dose 1.
Reaction of 1 with ethyl cyanoacetate in the presence of catalytic amount of piperidine furnished the chromene derivative (12), while its reaction with ethyl cyanoacetate in the presence of ammonium acetate gave the quinoline derivative (13).
Morpholine undergoes most chemical reactions typical for other secondary amines, though the presence of the ether oxygen withdraws electron density from the nitrogen, rendering it less nucleophilic (and less basic) than structurally similar secondary amines such as piperidine.
The structure of methadone, unlike morphine, pethidine and fentanyl, lacks a piperidine ring, but like each of these compounds, it retains a phenylpropylamine structure (Figure 1) and some morphine-like conformers of l-methadone (the active isomer) have been proposed.