, an alkaloid derived from black pepper increases serum response of beta carotene during 14 days of oral beta carotene supplementation.
NUTRITIONIST Seki Tijani says piperine
, the substance that gives pepper its punch, helps your body absorb nutrients from food, has heart protective properties and can boost levels of the brain's feelgood chemical serotonin, improving mood, sleep and appetite.
One new topical bioavailability enhancer is tetrahydropiperine or THP, a derivative of pungent alkaloid piperine
extracted from the fruits of the black pepper plant.
, a component of black pepper, inhibits adipogenesis by antagonizing PPARgamma activity in 3T3-L1 cells.
The supplement contained curcumin, piperine
, epigallocatechin gallate, alpha-lipoic acid, n-acetylcysteine, B vitamins, vitamin C, and folate.
Studies on the in vitro absorption of spice principles curcumin, capsaicin and piperine
in rat intestines.
A study published in Molecular Nutrition & Food Research (Special Issue: Resveratrol - Current Status and Outlook) found the absorption of resveratrol was increased significantly when combined with piperine
(black pepper extract).
Pepper warms the skin and also contains piperine
which increases the amount of pain-killing endorphins in the brain.
It is considered that concomitant administration of curcumin and piperine
significantly increases the serum concentration of curcumin, due to inhibition of hepatic and intestinal glucuronidation by piperine
(Shoba et al.
The current study examines the effect of a medical food cocktail consisting of the dietary supplements curcumin, piperine
, epigallocatechin gallate, [alpha]-lipoic acid, N-acetylcysteine, B vitamins, vitamin C, and folate on cognitive functioning and the AD hallmark features and amyloid-beta (A [beta]) in the Tg2576 mouse model of the disease.
The formula contains ForsLean, Sabinsa's patented extract from the roots of Coleus forskohlii (standardized to contain the diterpene forskolin 10%); GarCitrin, a patented extract from Garcinia cambogia fruit containing hydroxycitric acid (HCA) and garcinol; and BioPerine, a patented extract from black pepper fruit and a bioavailability enhancer containing the alkaloid piperine
Bisalkaloids such as dipiperamides A-C (67-71) were isolated from the white pepper (Piper nigrum) along with piperine