Also found in: Thesaurus, Encyclopedia, Wikipedia.


A crystalline solid, C17H19NO3, extracted from black pepper and used as flavoring and as an insecticide.

[Latin piper, pepper; see pepper + -ine.]


(ˈpɪpəˌraɪn; -rɪn)
(Elements & Compounds) a crystalline insoluble alkaloid that is the active ingredient of pepper, used as a flavouring and as an insecticide. Formula: C17H19NO3
[C19: from Latin piper pepper]


(ˈpɪp əˌrin, -ər ɪn)

a white, crystalline alkaloid, C17H19NO3, obtained from pepper: used as an insecticide.
[1810–20; < Latin piper pepper + -ine1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.piperine - derived from pepper (especially black pepper); source of the hotness of black and white pepper
black pepper, common pepper, Madagascar pepper, pepper, Piper nigrum, white pepper - climber having dark red berries (peppercorns) when fully ripe; southern India and Sri Lanka; naturalized in northern Burma and Assam
chemical irritant - a substance producing irritation
References in periodicals archive ?
Piperine, a component of black pepper, has been found to inhibit adipogenesis by antagonizing PPAR[gamma] activity in pre-adipocyte cells.
Curcuminoids were administered at a daily dose of 1 g, and were co-supplemented with piperine (10 mg/day) in order to boost oral bioavailability.
Piperine, an alkaloid from black pepper, inhibits the growth and motility of TNBC and enhances radiotherapy in vitro.
Tenders are invited for Supply of Drugs/Medicine Part- I,Tab All- ransretinoic Acid 10 mg,Tab Anastrazole 1 mg,Tab Blclutamlde 50 mg,Tab Cefpodoxime 200 mg,Tab Curcuminoids 5QQ mg + Piperine 5 mg,Tab Dasatimb 20 mg,Tab Dexamethasone 4 mg,Tab Erlotinib 100 ma,Tab Ethamsylate 5QQ mg,etc.
Piperine can interfere with the formation of new fat cells, this reaction is knows as adipogensis, which results in decreasing the size of the waist, cholesterol levels and body fat.
Bisalkaloids such as dipiperamides A-C (67-71) were isolated from the white pepper (Piper nigrum) along with piperine and piperylin.
Piperine and Quercetin are also included in the formulation to further enhance metabolism of the encapsulated curcumin.
21,26) BCM-95[R] was also more than six times as bioavailable as a leading mixture of curcumin that was combined with two other natural products, lecithin and piperine.
To increase absorption, supplements often contain curcumin combined with piperine (black pepper extract).
The culture of breast epithelial (MCF 10A) cells was initiated and treated with PhIP in the presence and absence of antioxidants namely ascorbic acid (AsA), Glutathione (GHS), N-acetyl-cysteine (NAC), alpha-tocopherol (Vitamin E), [61-gingerol, [10]-gingerol, lycopene, Vitamin K3, Piperine and Curcumin for 24 hours, The interaction of PhIP and phytochemicals were evaluated by cell proliferation assay; and for DNA damage by comet assay.
Of the various plant components described, piperine is present in Piper species fruits.