plasma cell


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Related to plasma cell: mast cell, Lymphocytes, plasma cell myeloma, plasma cell mastitis, plasma cell dyscrasia

plasma cell

n.
Any of various short-lived cells that develop from activated B cells and secrete large numbers of antibodies. They are found chiefly in the bone marrow, spleen, and lymph nodes. Also called plasmacyte.

plas′ma cell`


n.
an antibody-secreting cell, derived from B cells, that plays a major role in antibody-mediated immunity. Also called plas•ma•cyte (ˈplæz məˌsaɪt)
[1885–90]

plasma cell

A cell that produces antibodies as part of an immune response. B cells develop into plasma cells. See Note at antibody.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.plasma cell - a cell that develops from a B lymphocyte in reaction to a specific antigenplasma cell - a cell that develops from a B lymphocyte in reaction to a specific antigen; found in bone marrow and sometimes in the blood
lymph cell, lymphocyte - an agranulocytic leukocyte that normally makes up a quarter of the white blood cell count but increases in the presence of infection
plasmablast - the precursor of a plasma cell
References in periodicals archive ?
Most medical problems related to multiple myeloma are caused by the build-up of abnormal plasma cells in the bone marrow and the presence of paraprotein in the blood or in the urine.
While calcium signalling typically controls a wide range of cellular processes that allow cells to adapt to changing environments, it was found to inhibit the expression of the membrane proteins essential for plasma cell formation.
Nonsecretory myelomas are defined by a clinical and anatomical diagnosis of plasma cell dyscrasia with un detectable monoclonal protein in the serum (1).
This EuroFlow[TM] tube proved sufficient for the specific identification, enumeration and discrimination between normal/reactive and aberrant plasma cells, being used for the initial screening of Plasma Cell Dyscrasias.
Per these criteria, the increased IgG4 plasma cells should also be present in the setting of previously described lymph node histology: follicular hyperplasia, interfollicular/immunoblastic expansion, progressive transformation of germinal centers, plasma cell Castleman disease-like, and inflammatory pseudotumor-like.
Abnormal plasma cells secrete abnormal immunoglobulins that can be detected monoclonally (M peak) in serum and/or urine via electrophoresis.
Tokyo, Apr 22, 2011 - (JCN Newswire) - An article in Science Signaling by researchers at the RIKEN Research Center for Allergy and Immunology (RCAI) has clarified for the first time the mechanism governing differentiation of B cells into antibody-producing plasma cells.
The plasma cell has been designed to be easy to operate and simple to maintain with the added benefit of being compact - a good solution for a small production facility perhaps.
The silenced gene profile was compared and contrasted to normal plasma cells, which are highly specialised and for which growth and lifetime is tightly controlled.
Postinflammatory tumors of the lung; report of four cases simulating xanthoma, fibroma, or plasma cell tumor.
Patients with MGUS are, by definition, asymptomatic and have low levels of plasma cells (less than 10% in bone marrow), but a proportion of these patients will evolve over time.
Histologic endometritis--defined as the presence of at least five neutrophils in the superficial endometrial epithelium per 400X field and at least one plasma cell per 120X field of endometrial tissue--is common in women with lower genital tract infection who do not have signs or symptoms of acute pelvic inflammatory disease (PID), but there are conflicting data regarding whether treatment for the histologic diagnosis is warranted, said Dr.