renin

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Related to plasma renin activity: aldosterone

re·nin

 (rē′nĭn, rĕn′ĭn)
n.
An enzyme released by the kidneys that cleaves a plasma protein to produce an inactive form of angiotensin which is then converted to an active form that raises blood pressure.

[Latin rēnēs, kidneys + -in.]

renin

(ˈriːnɪn)
n
(Biochemistry) a proteolytic enzyme secreted by the kidneys, which plays an important part in the maintenance of blood pressure
[C20: from reni- + -in]

re•nin

(ˈri nɪn)

n.
a proteolytic enzyme secreted by the kidneys that is involved in the release of angiotensin.
[< German Renin (1897) = Latin rēn(ēs) kidneys + German -in -in1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.renin - a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure
peptidase, protease, proteinase, proteolytic enzyme - any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis
Translations

re·nin

[MIM*179820]
n. renina, enzima segregada por el riñón que interviene en la regulación de la presión arterial.
References in periodicals archive ?
Moreover, the observed aldosterone increases in these patients appeared to be relatively independent of presenting diagnosis (ST-elevated vs non-ST-elevated MI), degree of LV function, clinical risk factors, baseline or change in blood pressure, plasma renin activity, and natriuretic peptide concentrations.
A discrepancy between the effects of a single oral dose of captopril on blood pressure, plasma renin activity, and serum angiotensin-converting enzyme levels.
Our patient presented with hypertension, persistent hypokalemia, metabolic alkalosis, low plasma renin activity, high levels of serum aldosterone, and a high aldosterone/renin ratio that suggested primary aldosteronism.
To evaluate a patient who has an adrenal mass and hypertension and/or hyperkalemia, the physician should measure plasma aldosterone concentration and plasma renin activity (after the patient has been upright for at least 2 hours).
Essential hypertension probably represents a heterogeneous set of disorders that may involve the interplay of a number of factors linked to essential hypertension, including genetic and environmental factors, salt sensitivity, endocrinologic factors manifest in variations in plasma renin activity, cell membrane defect, and insulin resistance (14).
Plasma Renin Activity and Angiotensinogen M235T Polymorphism are Determinants of Aldosterone Escape in Patients with Systolic Heart Failure
Aliskiren moderately reduced blood pressure, substantially reduced plasma renin activity, and produced a compensatory increase in plasma renin concentration," they wrote.
Screening for primary aldosteronism in essential hypertension: diagnostic accuracy of the ratio of plasma aldosterone concentration to plasma renin activity.
Effect of lead on renin-angiotensin and kininergic systems: In a meta-analysis of the earlier published studies, Vander (71) found increased plasma renin activity and renal tissue renin content in young rats after several weeks of lead exposure.
By inhibiting renin at the top of the RAS, SPP100 decreases the system's activity, as measured by Plasma Renin Activity.

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