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plasmablast

   Also found in: Medical 0.01 sec.
plas·ma·blast  (plzm-blst)
n.
The precursor or stem cell of a plasma cell.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.plasmablast - the precursor of a plasma cell
plasma cell, plasmacyte - a cell that develops from a B lymphocyte in reaction to a specific antigen; found in bone marrow and sometimes in the blood


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The characteristic features are interfollicular plasmablasts that express the HHV8 latent nuclear antigen (LANA).
As it was noted that in HIV-associated MCD, KSHV infects mu/lambdarestricted plasmablasts located in the mantle zone (and importantly, such cells express the CD20 surface antigen), separate reports regarding 12 patients treated with rituximab have appeared in the literature over the last 6 years.
[1] For the plasmacytic cell series, experts recommended that the terms plasmablast, proplasmacyte, and plasmacyte identify these cells.
 
 
 
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