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A cell that is a precursor of a plasma cell and develops from an activated B cell.
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Noun1.plasmablast - the precursor of a plasma cell
plasma cell, plasmacyte - a cell that develops from a B lymphocyte in reaction to a specific antigen; found in bone marrow and sometimes in the blood
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The disease affects multiple organ systems and is characterized by a distinct microscopic appearance of diseased organs, including the presence of IgG4-positive plasmablast cells.
The plasmablast expansion is oligoclonal, not polyclonal," Dr.
Plasma cell population predominantly comprised of plasmablast, intermediate plasma cells and few mature forms.
Arrays were rinsed in PBS for 15 minutes before use and incubated with 100 [micro]L cell culture supernatants of plasmablast assays for 1 hour at 37[degrees]C.
11] Plasma cells or plasmablasts, both known to secrete high amounts of antibodies, were found in perivascular, interstitial, and Virchow-Robin spaces of brain, providing a histopathological explanation for the intrathecal synthesis of antibodies noted in anti-NMDAR encephalitis.
IgG4 levels and plasmablasts as a marker for IgG4-related disease (IgG4-RD).
Plasmablasts isolated from patients during or immediately after recovery from acute DENV infection produced antibodies that cross-neutralized Zika virus in cell culture (35) and were protective in a mouse model of Zika virus infection (18).
The investigators demonstrated that AD is accompanied by systemic expansion of transitional and chronically activated memory B cells, plasmablasts, and IgE-expressing memory B cells in both skin and blood.
Aspirates from multiple myeloma show numerous atypical plasmablasts with binucleate and trinucleate atypical plasma cells with high nuclear/cytoplasmic ratio with prominent nucleoli (Figure D).
Numerous mott cells and occasional plasmablasts were also noted (Figure 2).
Plasmablasts as a biomarker for IgG4-related disease, independent of serum IgG4 concentrations.