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Related to plasmid: Plasmid DNA


A circular, double-stranded unit of DNA that replicates within a cell independently of the chromosomal DNA. Plasmids are most often found in bacteria and are used in recombinant DNA research to transfer genes between cells.


(Genetics) a small circle of bacterial DNA that is independent of the main bacterial chromosome. Plasmids often contain genes for drug resistances and can be transmitted between bacteria of the same and different species: used in genetic engineering
[C20: from plasm + -id1]


(ˈplæz mɪd)

a strand or loop of DNA that exists independently of the chromosome in bacteria and yeast and that is capable of genetic replication: used in recombinant DNA procedures as a vehicle of gene transfer.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.plasmid - a small cellular inclusion consisting of a ring of DNA that is not in a chromosome but is capable of autonomous replication
cellular inclusion, inclusion body, inclusion - any small intracellular body found within another (characteristic of certain diseases); "an inclusion in the cytoplasm of the cell"
References in periodicals archive ?
Recently we have developed cutting edge abilities to access a plasmid population (plasmidome) of a given microbial community, and applied them to rumen microbial communities.
coli TOP10 by electroporation of the total plasmid extracted from YD472.
They were initially looking for diatom DNA sequences that allowed for plasmid replication but instead identified a yeast plasmid that replicates in diatoms and functions like an artificial chromosome.
If a special plasmid composed of the glycoprotein-160 HIV gene, and the two reporter genes Green Fluorescence Protein and Firefly Luciferase, is able to be successfully inserted into human T-cells to create cells that look like HIV, then tests can be performed and data can be collected to analyze the effectiveness of the therapeutic aptamer-small interfering RNA(siRNA) chimera, a new smart-bomb approach, to destroy the HIV cell.
The topics include operator-repressor titration: stable plasmid maintenance without selectable marker genes, analytical tools in minicircle production, magnetofection of minicircle DNA vectors, the episomal expression of minicircles and conventional plasmids in mammalian embryos, and the influence of the extracellular matrix in the increased efficiency of minicircles versus plasmids under gene electrotransfer sub-optimal conditions.
Large-scale production of plasmid DNA (pDNA) for medical use is however a new field in biopharmacy.
The biggest plasmid is highly homologous to a previously sequenced plasmid isolated from a horse and carrying additional multi-drug resistance genes.
RecipharmCobra Biologics, Keele, UK, a international manufacturer of biopharmaceuticals, has been granted European and United States patents for its novel plasmid maintenance system.
However, majority of the known plasmid curing agents including acridine orange, ethidium bromide and sodium dodecyl sulphate are toxic or mutagenic and hence unsuitable for therapeutic applications.
For example, the Electro Bolt plasmid allows you to shoot lightning from your hands to electrocute enemies while Insect Swarm gives you the power to send a swarm of bugs to attack enemies.
The ease and reproducibility of plasmid DNA isolation from bacteria permits numerous labs to conduct molecular biology experiments and greatly accelerates progress in understanding complex biological processes.
Wyeth Holdings Corporation (Madison, NJ) has patented expression of the lipidated form of the peptidoglycan-associated protein (PAL) of gram-negative bacteria achieved through the use of a plasmid containing a tightly regulated promoter.