Also found in: Thesaurus, Medical, Encyclopedia, Wikipedia.
Related to plasmin: plasminogen, fibrinogen


A proteolytic enzyme that is formed from plasminogen in blood plasma and dissolves the fibrin in blood clots. Also called fibrinolysin.


(Biochemistry) a proteolytic enzyme that causes fibrinolysis in blood clots


(ˈplæz mɪn)

an enzyme in the blood that dissolves blood clots by breaking down fibrin. Also called fibrinolysin.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.plasmin - an enzyme that dissolves the fibrin of blood clots
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
plasminogen - an inactive form of plasmin that occurs in plasma and is converted to plasmin by organic solvents
References in periodicals archive ?
Once activated, plasmin breaks down fibrin, resulting in the formation of D-dimer, a fibrin degradation product and a clinical marker of fibrinolysis.
Under physiologic conditions, the conversion ofplasminogen to plasmin is regulated by activators such as tissue plasminogen activator (tPA), urokinase plasminogen activator (uPA), and FXIIa.
6 Troponin I, ng/mL ND ND Coagulation Prothrombin time, s ND ND International normalized ratio, s ND ND Partial thromboplastin time, s ND ND Dimerized plasmin fragment, ng/mL ND ND Patient value, day of hospitalization ([dagger]) Test 4 5 Hematologic White blood cell count, x [10.
Many pathogenic bacteria have been shown to bind host plasmin to disseminate and cause disease, and we hypothesize that Escherichia coli surface-exposed Lpp can bind plasminogen.
Lysteda is a nonhormonal lysine analog that acts as a competitive plasmin inhibitor; it is not a contraceptive.
Plasmin is involved in the destruction of the extracellular matrix which is rich in fibrin.
Washington, March 9 ( ANI ): Doctors use drugs that activate plasmin, a powerful blood enzyme that disposes of blot clots, to treat patients who suffer heart attack or stroke.
21) Agents that preserve hemostasis through plasmin inhibition include Epsilon aminocaproic acid (EACA or Amicar[R]), tranexamic acid (TA), and aprotonin.
Likewise, in the IBD patients with increased disease activity, plasminogen activator inhibi-tor-1 levels are increased and it is a potent inhibitor of fibrinolysis, working via inhibiting plasmin generation (5).
Plasmin splits fibrin, fibrinogen, factor V and factor VIII inducing a "systemic lytic state" (18,19).
Plasmin hydrolyzes the casein in milk, causing proteolysis that leads to poor quality in milk products.
Microplasmin is a truncated form of the natural human protein plasmin.