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Related to plasmin: plasminogen, fibrinogen


A proteolytic enzyme that is formed from plasminogen in blood plasma and dissolves the fibrin in blood clots. Also called fibrinolysin.


(Biochemistry) a proteolytic enzyme that causes fibrinolysis in blood clots


(ˈplæz mɪn)

an enzyme in the blood that dissolves blood clots by breaking down fibrin. Also called fibrinolysin.
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.plasmin - an enzyme that dissolves the fibrin of blood clots
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
plasminogen - an inactive form of plasmin that occurs in plasma and is converted to plasmin by organic solvents
References in periodicals archive ?
1],[2] Recent studies suggested that prolonged fibrinolytic activity from delayed activation of plasmin beyond the initial surgical trauma might be a potential cause for HBL.
In addition to these strategies, there is a new recommendation for managing refractory PPH: tranexamic acid, which works by binding to lysine receptors on plasminogen and plasmin, inhibiting plasmin-mediated fibrin degradation.
Tranexamic acid (Trans-4-aminomethylcyclohexanecarboxylic acid) [TNA], is a plasmin inhibitor used to prevent abnormal fibrinolysis to reduce blood loss.
She had sinus tachycardia on electrocardiography, higher values of serum dimerized plasmin fragment D (D-dimer) (5000 ng/mL) and an enlarged pulmonary artery with mild cardiomegaly on the chest X-ray.
And, to balance that dissolving process, you also produce inhibitors of plasmin.
TA is a synthetic lysine analog that is a competitive inhibitor of plasminogen and plasmin, inhibiting fibrinolysis by preventing conversion to plasmin (Haspl, Oremus, Sostaric, & Trkulja, 2014; Wei & Liu, 2015).
The plasmin cleaves Hageman factor in a way that results in a strong release of kallikrein but a weak release of thrombin.
A lumbar puncture was then performed which prompted the performance of a rapid plasmin reagent (RPR).
Bovine pancreatic chymotrypsin is the active ingredient in Quimotripsyn[R]--Virbac Laboratories, whose action increases plasmin, a proteolytic enzyme of endothelial origin that is responsible for lysing excess of fibrin from the inflammatory process and is considered as the key of fibrinolysis (16).
Tissue plasminogen activator (tPA) released by the vessel wall converts plasminogen, a proenzyme in blood and tissue fluids, into plasmin which results in dissolution of fibrin clot within the circulation.
In addition, we did not assess the levels of heparin sulfate and plasmin activity in breast cysts fluid that may reflect the function of epithelial cells forming cysts [30, 31].
Although multiple enzymes and other agents have been examined in animal models, only hyaluronidase, plasmin and microplasmin have had significant clinical experience reported.