polyene


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pol·y·ene

 (pŏl′ē-ēn′)
n.
An organic compound containing two or more carbon-carbon double bonds.

polyene

(ˈpɒlɪˌiːn)
n
(Elements & Compounds) a chemical compound containing a chain of alternating single and double carbon-carbon bonds
References in periodicals archive ?
Amphotericin B is a polyene macrolide broad spectrum antibiotic with excellent anti-fungal properties12.
Sterol content and polyene antibiotic resistance in isolates of Candida krusei, Candida parakrusei, and Candida tropicalis.
For many years, the standard treatment for candidiasis has been amphotericin B, a polyene fungicidal agent.
Retinal, also named retinaldehyde, is a polyene chromophore and is the basis for animal vision allowing the conversion of light into metabolic energy.
The Mechanism of antifungal action of a new polyene macrolide antibiotic antifungalmycin 702 from streptomyces padanus JAU4234 on the rice sheath blight pathogen Rhizoctonia solani.
Beta-carotene (the main precursor for vitamin A, theoretically produces two molecules of retinal (central cleavage) which is reduced to retinal or oxidized (irreversibly) to retinoic acid, while eccentric cleavage only gives rise to apocarotenals in which the conjugated polyene is successfully shortened by Beta-oxidation to one molecule of retinoic acid (Faullks & Southon, 2001).
Postantifungal effects of echinocandin, azole, and polyene antifungal agents against Candida albicans and Cryptococcus neoformans.
Most of the latter patients received conventional liver-protecting treatment, for instance, polyene phosphatidylcholine, tiopronin.
As was done in this case, practice guidelines recommend a longer duration of polyene antimycotic induction for patients with cryptococcomas than for those without (4), and longer courses of therapy are commonly described for infections caused by C.
The electron-rich conjugated system of the polyene is believed to afford antioxidant and free radical scavenging activity and these pharmacological effects were attributed to health benefits offered by carotenoids [33].
Amp B a polyene antibiotic is the second line treatment for leishmaniasis, binds specifically to ergosterol, the main sterol present of Leishmania, trypanosome cruzi and fungi [15].