polymerase chain reaction


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polymerase chain reaction

n. Abbr. PCR
A technique for amplifying DNA sequences in vitro by separating the DNA into two strands and incubating it with oligonucleotide primers and DNA polymerase. It can amplify a specific sequence of DNA as many as one billion times and is important in biotechnology, forensics, medicine, and genetic research.

pol′ymerase chain′ reac`tion



n.
the laboratory production of numerous copies of a gene by separating the two strands of the DNA containing the gene segment, marking its location with a primer, and using a DNA polymerase to assemble a copy alongside each segment and continuously copy the copies. Abbr.: PCR
Translations
amplification en chaîne par polymérase
References in periodicals archive ?
Performance of this polymerase chain reaction method was compared against the microscopy results.
The polymerase chain reaction, or PCR, found its way into many areas in biology very soon after its invention by the American Kary Mullis in 1983, who received a Nobel Prize for his discoveries in 1993.
Nested polymerase chain reaction (PCR) VZV DNA results were negative both in the personal air samples and in saliva.
None of the vaccine recipients had HPV 16 or CIN on at least two consecutive polymerase chain reaction tests, meaning that the vaccine was 100% effective, Dr.
All diagnoses were confirmed by use of a more sophisticated laboratory test called polymerase chain reaction assay.
DNA was isolated from feathers and the amplification of the CHD gene was performed with the following sets of polymerase chain reaction primers: 2550F/2718R and P2/P8.
Tokyo, Japan, Mar 27, 2006 - (JCN) - Takara Bio will launch the Thermal Cycler Dice Real Time System, a real-time polymerase chain reaction (PCR) system, on April 3.
21) Saboor's group found Mycobacterium species DNA on polymerase chain reaction in the bronchopulmonary lavage fluid of 70% of sarcoid patients, compared with only 9% of controls.
MAUI, HAWAII -- Polymerase chain reaction testing is now important for diagnosing neonatal herpes simplex encephalitis, Dr.
The chemicals amplify the minuscule amount of DNA to a measurable quantity via a process called the polymerase chain reaction, or PCR (SN: 10/23/93, p.

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