polymyxin


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pol·y·myx·in

 (pŏl′ē-mĭk′sĭn)
n.
Any of various mainly toxic antibiotics derived from strains of the soil bacterium Bacillus polymyxa and used to treat various infections with gram-negative bacteria.

[New Latin polymyxa, specific epithet (poly- + Greek muxa, slime) + -in.]

polymyxin

(ˌpɒlɪˈmɪksɪn)
n
(Pharmacology) any of several polypeptide antibiotics active against Gram-negative bacteria, obtained from the soil bacterium Bacillus polymyxa
[C20: from New Latin Bacillus polymyxa; see poly-, myxo-, -in]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.polymyxin - any of several toxic antibiotics obtained from a particular soil bacterium
antibiotic, antibiotic drug - a chemical substance derivable from a mold or bacterium that can kill microorganisms and cure bacterial infections; "when antibiotics were first discovered they were called wonder drugs"
References in periodicals archive ?
M2 PHARMA-March 6, 2018-MicuRx awarded CARB-X's grant for innovative polymyxin antibiotic MRX-8
M2 EQUITYBITES-March 6, 2018-MicuRx awarded CARB-X's grant for innovative polymyxin antibiotic MRX-8
All isolates of acinetobacter baumannii (n=32) were resistant to ampicillin, ceftriaxone and ceftazidime but sensitive to polymyxin B.
Consumption of quinolones (ciprofloxacin) did not change and a reduction in the use of polymyxin was observed.
Most of the 1st and 2nd generation cephalosporins were resistant to biofilm producers whereas carbapenem, polymyxin and tetracycline came out to be effective drugs against biofilm producers.
The following antibiotics were included: amoxicillin, amoxicillin-clavulanic acid (AMC), piperacillin, piperacillin-tazobactam (TZP), mezlocillin, mezlocillin-sulbactam (MSU), cefazolin, cefuroxime, ceftriaxone, cefotaxime, ceftazidime, cefoperazone, cefoperazone-sulbactam (CSL), cefepime, aztreonam, moxalactam, imipenem, meropenem, panipenem, ertapenem, gentamycin, amikacin, tetracycline, minocycline, tigecycline, ciprofloxacin, levofloxacin, nitrofurantoin, fosfomycin, polymyxin B, and colistin.
Rapid Detection of Polymyxin Resistance in Enterobacteriaceae
7 Neomycin S Polymyxin B Sulphate & Bacitracin, Ocpupol Eye Oint 5gm NO 1650
Reference susceptibility testing by broth microdilution showed that the isolates had a colistin (also known as polymyxin E) minimum inhibitory concentration (MIC) of 2 [micro]g/ml, and polymyxin B MIC of 4 [micro]g/ml.
Adverse reactions associated with systemic polymyxin therapy.
Commonly used topical agents include bacitracin, cefazolin, ciprofloxacin, gentamycin, impenem, mupirocin, neomycin, polymyxin, retapamulin, and benzoyl peroxide.
Ceftazidime (CAZ, 30 [micro]g), imipenem (IMP, 10 [micro]g), meropenem (MEM, 10 [micro]g), ciprofloxacin (CIP, 5 [micro]g), aztreonam (ATM, 30 [micro]g), polymyxin B (PB, 300 units), gentamicin (GM, 10 [micro]g), vancomycin (30 [micro]g), piperacillin (PIP, 100 [micro]g), ceftriaxone (CRO, 30 [micro]g), and amikacin (AMK, 30 [micro]g) purchased from MAST, Merseyside, UK, were used, according to CLSI (Clinical Laboratory Standard Institute) recommendations and the disk diffusion method was applied to determine antibiotic susceptibility.