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Related to polynucleotide: Polynucleotide Kinase, Polynucleotide phosphorylase


 (pŏl′ē-no͞o′klē-ə-tīd′, -nyo͞o′-)
A polymeric compound, usually DNA or RNA, consisting of a number of nucleotides.


(Biochemistry) biochem a molecular chain of nucleotides chemically bonded by a series of ester linkages between the phosphoryl group of one nucleotide and the hydroxyl group of the sugar in the adjacent nucleotide. Nucleic acids consist of long chains of polynucleotides


(ˌpɒl iˈnu kli əˌtaɪd, -ˈnyu-)

a sequence of nucleotides, as in DNA or RNA, bound into a chain.
References in periodicals archive ?
Members of the AID/APOBEC family of enzymes deaminate cytosine (C) to uracil (U) in the context of a polynucleotide substrate.
Patent Application Number 13/336,028 entitled, "In Vivo Polynucleotide Delivery Conjugates Having Enzyme Sensitive Linkages.
Mark Glover, his graduate student Zahra Havali-Shahriari and post-doctoral fellow Nicolas Coquelle solved the structure of a DNA repair enzyme called polynucleotide kinase/phosphatase, or PNKP.
6,307,039 (Method for Analyzing a Polynucleotide Containing a Variable Sequence and a Set or Array of Oligonucleotides Thereof), 6,770,751 (Method for Analyzing a Polynucleotide Containing a Variable Sequence and a Set or Array of Oligonudeotides Thereof) and 7,192,707 (Method for Analyzing Polynucleotide Targets Using Tethered Oligonucleotide Probes).
It extends to antisense polynucleotide constructs and to structures that increase the stability of antisense RNA, as well as non-human organisms containing antisense constructs, among others.
For instance, each nucleic acid that is added to a polynucleotide can have a different conformation.
Washington, June 18 (ANI): An enzyme, called human polynucleotide phosphorylase or hPNPaseold-35, discovered in 2003, could play a major role in preventing melanoma-the most serious type of skin cancer.
Tokyo, Japan) has patented a protein having saponin-decomposing activity, more specifically a protein which can decompose a glycoside having soyasapogenol B as an aglycone to produce soyasapogenol B, a polynucleotide encoding such a protein, and a method of producing soyasapogenol B on a large scale using the same.
4,994,373 ("Method and Structures Employing Chemically-Labeled Polynucleotide Probes").
8,338,100 "Isolated Genomic Polynucleotide Fragments from Chromosome 12 that Encode Human Carboxypeptidase M" is directed to the region of a genomic sequence encoding a protein associated with monocyte to macrophage differentiation.
She is a founding team member for the International Consortium for Polynucleotide Synthesis, Inc.
AAL was incorporated in July 2003 for product research and development in the field of nonphotolithographic arrays of polynucleotide sequences and instruments.