It also reviews key players involved in the therapeutic development for Portal Hypertension
and special features on late-stage and discontinued projects.
Khan's interest include Hepatitis C and B, Cirrhosis of the liver, portal hypertension
, liver cancer, peticulcer disease, colitis, GI Maligancies and pancreatobility disease etc.
The Middlesbrough youngster suffers from a variety of conditions including portal hypertension
, congenital hepatic fibrosis, polycystic kidney and Caroli disease.
Patients with chronic hepatitis C who develop cirrhosis with severe portal hypertension
are at greater risk of progressing to liver decompensation within the first 5 years of treatment, even if they show a sustained virologic response to therapy, a cohort study has found.
Core vascular-based procedures include catheter-directed treatment of peripheral arterial disease, dysfunctional hemodialysis access, vascular malformations, arterial bleeding, portal hypertension
, veno-occlusive disorders, venous insufficiency, varicoceles and tumors (eg, arterial embolization, gene therapy), in addition to placement of temporary and permanent vascular access catheters.
Since then she has been further diagnosed with chronic liver disease, decompensate portal hypertension
, and an umbilical hernia.
Upper gastrointestinal haemorrhage has a variety of causes (Table 1) and is the commonest complication of peptic ulceration and portal hypertension
Pathogenesis of intrahepatic, non-tumorous portosystemic shunts may be due to portal hypertension
Thromboxane A2 which is released from these cells leads to portal hypertension
by causing increased intrahepatic resistance.
The need to distinguish between NASH and simple steatosis is essential, as patients with NASH can go on to develop portal hypertension
com)-- Portal Hypertension
Global Clinical Trials Review, H1, 2013
Complications of portoenterostomy include: ascending bacterial cholangitis, cirrhosis, portal hypertension
, metabolic and nutritional consequences of cholestasis, intrahepatic cyst formation, hepatopulmonary syndrome, pulmonary hypertension, and malignant change in the liver (rare).