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Related to postsynaptic: Postsynaptic density, postsynaptic membrane, Postsynaptic neuron


Situated behind or occurring after a synapse: postsynaptic neurons.

post′syn·ap′ti·cal·ly adv.


1. (Biology) cytology occurring after synapsis
2. (Anatomy) anatomy located on the distal side of a synapse


(ˌpoʊst sɪˈnæp tɪk)

being or occurring on the receiving end of a discharge across a synapse.
References in periodicals archive ?
With epileptic seizures being primarily mediated by the neurotransmitter glutamate, the agent is a highly selective, noncompetitive AMPA receptor antagonist that reduces neuronal hyperexcitation associated with seizures by targeting glutamate activity at postsynaptic AMPA receptors.
Methods: Field excitatory postsynaptic potentials (fEPSPs), spontaneous excitatory postsynaptic currents (sEPSCs) and miniature spontaneous excitatory postsynaptic currents (mEPSCs) were recorded, by using in vitro field potential electrophysiology and whole-cell patch clamp techniques in acute hippocampal slices from rats.
Hyperprolactinemia associated with the use of selective serotonin reuptake inhibitors (SSRI) is explained by the direct stimulation of postsynaptic serotonergic receptors in the hypothalamus and the serotonergic inhibition of dopamine, which is a prolactin inhibiting factor (4).
Of interest, he notes that the width of the synapse is 1 millionth of a centimeter and that the average neurotransmitter binding time to a postsynaptic receptor last 1 thousanth of a second.
These include genes that are active in pathways controlling synaptic plasticity - a function essential to learning and memory - and pathways governing postsynaptic activity, such as voltage-gated calcium channels, which are involved in signaling between cells in the brain.
The released neurotransmitter binds to postsynaptic receptors, leading to a response in the postsynaptic neuron.
They have been found on both pre-and postsynaptic cells, and are expressed in epithelium, connective and muscle tissues.
On the other hand, another implication could be considered for these reports which is that baclofen affects two presynaptic and postsynaptic types of receptors and the obtained responses are the result of activities of these presynaptic and postsynaptic receptors.
For this change to occur, the presynaptic and postsynaptic neurons must be activated during the release of dopamine.
These are flaccidity/detumescence, an active smooth-muscle process with vasoconstriction of the arterial bed mainly a postsynaptic alpha-sympathetic function but with contributions from other neurovascular factors, including angiotensin II, prostaglandin E[F.
Metabotropic receptors are both slower and longer acting than ionotropic receptors, for they activate a second messenger cascade system that can result in the opening of ion channels located elsewhere on the same postsynaptic membrane.
Neonicotinoids are neurotoxins, irreversibly and cumulatively binding to and blocking postsynaptic nicotinergic acetylcholine receptors in the central nervous system of insects.