Intrinsic adjuvanticity and propensity to be manipulated potentially make OMVs an ideal vaccine platform, particularly indicated when antigen combinations (for pathogens with genetic variability) and strong potentiation
of immunity (for the elderly and cancer) are needed.
Previous studies have shown that TEN facilitates the induction of long-term potentiation
(LTP), a cellular mechanism for learning and memory, and then exhibits a nootropic effect in healthy mice (Huang et al.
Exclusion criteria included significant tremor, musculoskeletal disorders that may confound assessment of motor function, previous deep brain stimulation, history of stroke, cerebellar, vestibular or sensory ataxia, women of childbearing potentiation
and any contraindications to 4-tesla MRI.
Detection of Ara-CTP following exposure to CPX-351 and potentiation
of action by fludarabine in leukemia cell lines using a bioluminescent bacterial biosensor
Ras-grf mice have defective long-term potentiation
(LTP), "a form of synaptic plasticity that is known to be important for learning and memory.
They are critical to the function of neural circuits that are required for inhibitory learning mechanism, long-term potentiation
in the hippocampus and long-term depression in the cerebellum.
Since then, more and more therapeutic properties of Chinese herbal polysaccharides have been gradually verified, in terms of immune potentiation
, antitumor, hypoglycaemic activity, anti-oxidation, anti-aging, anti-virus, gastrointestinal system protection, and so on.
Previous studies have shown that our ability to learn and form memories is due to an increase in synaptic communication called Long Term Potentiation
It does this by either increasing or decreasing the strength (receptor density) - becoming stronger with long-term potentiation
(LTP) and becoming weaker with long-term depression (LTD).
On the other hand the dynamic general or specific explosive movements that are typically performed during warm-up may induce a phenomenon called post-activation potentiation
(PAP) that enhances muscle power in the following 3-20 minutes (Gelen, 2010; Hilficker et al.
Furthermore, n-3 fatty acid deprivation during development resulted in marked decreases of synapsins and glutamate receptor subunits in the hippocampi of 18-day-old pups with concomitant impairment of long-term potentiation
, a cellular mechanism underlying learning and memory.
In step one, or potentiation
, at least two mutations arose that set the stage for the citrate-eating ability.