preclinical phase

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Related to preclinical phase: preclinical trial, preclinical study
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Noun1.preclinical phase - a laboratory test of a new drug or a new invasive medical device on animal subjects; conducted to gather evidence justifying a clinical trial
trial, run, test - the act of testing something; "in the experimental trials the amount of carbon was measured separately"; "he called each flip of the coin a new trial"
References in periodicals archive ?
However, through this strategic partnership our clients will have an opportunity to look beyond preclinical phase and utilize the whole pipeline of drug discovery with Phase 1-4 clinical studies, stated Dr.
Results show that ASD has a preclinical phase when detecting it may be difficult," explains Rebecca Landa, director of the Kennedy Krieger Institute's Center for Autism and Related Disorders and the study's lead author.
The first preclinical phase applies only in a research setting and outlines brain changes such as amyloid plaque buildup and nerve cell changes that may be present without significant symptoms in the patient.
Most of the developments are currently in the preclinical research phase, however there are already forty trials with patients underway--3 in Phase III, 24 in Phase II and 13 in Phase I--and 50 projects in the preclinical phase.
We can't begin to think about preventing this damage until we've learned more about the preclinical phase," Dr.
If these changes reflect early stage Alzheimer's disease, they suggest that Alzheimer's may have a preclinical phase that lasts for years and occurs even before the onset of mild cognitive impairment.
BioVectra's expertise includes preclinical phase I to phase III clinical trial material, active pharmaceutical ingredients, natural product extraction and purification and advanced intermediates.
There is no evidence that early screening reduces diabetic complications or that screening tests can detect diabetes during a preclinical phase.
HIV Therapeutics: Mymetics is in the preclinical phase, developing and testing peptides and other compounds that adhere to gp41 or the IL-2 receptor site without suppressing the immune system.
The company is also developing a transdermal form of the drug for both pre-dialysis and dialysis HPT patients; this delivery system is in the preclinical phase of development.
Even if still in a preclinical phase, Janus' unique triple TLR antagonist has potential therapeutic applications across multiple autoimmune diseases with high unmet medical need," said Grayson Lipford, Janus' co-founder and Chief Scientific Officer.