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An inactive compound that is converted by enzymes into a biologically active hormone.
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First off, why would the thyroid gland release a prehormone instead of just making the active T3 form?
It is then quickly converted by the liver to the prehormone 25(OH)D and then further converted in the kidneys to the hormone 1.
Vitamin D3 then circulates in the blood and is transported to the liver, where it is converted to 25-hydroxy-vitamin D [25(OH)D], This is often called a prehormone as it eventually gets converted in the kidneys and in many tissues to the hormone 1,25-dihydroxy-vitamin D (also called calcitriol, or activated vitamin D).
4) This prehormone is the body's main storage form of vitamin D, and the amount of calcidiol available to the body is what determines vitamin D status.
It is a precursor to a hormone, and this prehormone is responsible for making a very important regulator of cardiovascular processes," he said.