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Related to presynaptic: presynaptic membrane


Situated in front of or occurring before a synapse: a presynaptic nerve fiber; a presynaptic stimulus.


1. (Physiology) situated near to a nerve synapse
2. (Microbiology) (during meiosis) occurring before the pairing of chromosomes


(ˌpri sɪˈnæp tɪk)

being or occurring on the transmitting end of a discharge across a synapse.
References in periodicals archive ?
Lantheus Holdings announced "positive" new data from a Phase 2 study of LMI 1195, a fluorine-18 labeled tracer for use in cardiac positron emission tomography to assess myocardial presynaptic sympathetic nerve function.
Objective: In neurons, Endoplasmic reticulum (er) organelle shows physical continuity between dendrites, Cell body and axonal presynaptic terminals, And has been termed a neuron within a neuron .
A sufficient local buildup of calcium causes postsynaptic NGF release [12] which then leads to an increase in presynaptic vesicle cycling.
VMAT2 is a protein in the brain that packages neurotransmitters, such as dopamine, for transport and release in presynaptic neurons.
VMAT2 is a protein in the brain that packages neurotransmitters for transport and release in presynaptic neurons, concluded the company.
The analgesic effects of cannabinoids and their ligands are primarily mediated by the cannabinoid receptor 1 (CB1) via inhibition of presynaptic gamma-aminobutyric acid (GABA) and glutamatergic transmission.
One popular preparation is that of neuromuscular junctions (NMJs), which have simple connectivity between presynaptic motor neurons and postsynaptic muscles.
amp;nbsp;The key difference is their action on the dopamine transporter, which generally moves a lot of the dopamine in the synapse back into the presynaptic neuron - which reduces the amount of dopamine in the synapse, and dopamine signalling.
Propofol-induced area increase might be involved in the presynaptic pathway in GABAergic modification.
2+] to the presynaptic membrane and then neurotransmitters such as glutamate, acetylcholine, and GABA are released in the form of vesicles.
Mirtazapine is a presynaptic alpha-2 antagonist that also blocks the 5-HT2a, 5-HT2c, 5-HT3, and H-l receptors.