primary syphilis


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Related to primary syphilis: chlamydia, HPV

primary syphilis

n.
The first stage of syphilis, characterized by formation of a painless chancre at the point of infection and hardening and swelling of adjacent lymph nodes.
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Noun1.primary syphilis - the first stage; characterized by a chancre at the site of infection
lues, lues venerea, pox, syph, syphilis - a common venereal disease caused by the treponema pallidum spirochete; symptoms change through progressive stages; can be congenital (transmitted through the placenta)
References in periodicals archive ?
Placental transmission incidence is 70-100% for primary syphilis, 40% for early latent syphilis, and 10% for late latent syphilis (3).
In primary syphilis, increased fluorodeoxyglucose (FDG) accumulation could be seen at the site of inoculation or in the regional lymph nodes.
Some patients may report having a recent chancre--a painless, self-limiting ulcer in the genital area--which is characteristic of primary syphilis (see "Single nontender ulcer on the glans," J Fam Pract.
Out of total 20 patients with syphilis 3 had primary syphilis, 4 had secondary syphilis and 13 had latent syphilis during routine VDRL screening.
Primary syphilis occurring at the site of inoculation may present as a painless macule which often later ulcerates.
It came from a patient with primary syphilis and a history of herpes simplex virus 2, and a reactive RPR (1:2 serum dilution) that was collected 6 days before the SHC test.
Symptoms in primary syphilis may vary, however this stage is considered highly infectious.
Table 1 5 Stages of syphilis Stage Symptoms Primary syphilis Chancre in genitalia (often unnoticed) Secondary syphilis Maculopapular, non-tender rash; fever; lymphadenopathy; condyloma latum (genital) Latent syphilis Asymptomatic; serum nontreponemal and treponemal antibody tests are positive Tertiary syphilis Multiple organ-system involvement: Nerve involvement (deafness), aortic root dilation, aortitis, gummas (liver, bone, skin, spleen) Neurosyphilis Any stage can progress to neurologic involvement.
Primary syphilis was diagnosed in four cases, secondary syphilis in other four cases, and nine cases were classified as early latent syphilis.
5] It is important to note that sera from up to a third of patients with primary syphilis will be non-reactive when tested with non-treponemal (such as RPR) and treponemal-specific serological assays.
Primary syphilis may present as a painless genital ulcer 3-6 weeks after the infection is acquired (condylomatalata), this may be on cervix and go unnoticed.