proband


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Related to proband: propositus, consultand

pro·band

 (prō′bănd′, prō-bănd′)
[German Proband, person being tested, test subject, from Latin probandus, gerundive of probāre, to test; see prove.]

proband

(ˈprəʊbænd)
n
(Medicine) another name (esp US) for propositus2
[C20: from Latin probandus, gerundive of probāre to test]
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References in periodicals archive ?
Although the paternal grandmother could not be tested, because she was deceased, based on the fact that 6 of 7 siblings of the father and 8 nephews of the paternal grandmother had no TR[beta] gene mutation, it is likely that the mutation also occurred de novo in the father of the proband.
00 (combining day stay, surgical and anaesthetic costs) at our institution, initial proband DNA sequencing costs of A$500.
However, establishing a link between proband characteristics and psychiatric disorders in relatives would strengthen that suggestion.
The first analysis examined the impact of 5-year survival of the proband (i.
If a proband was found to have at least two siblings with alcohol dependence, the family was recruited for the second stage of the study.
In the case presented by Starr et al, in which the sister of the proband in the second generation was diagnosed with CVID, an ophthalmic examination or an electroretinogram (ERG), (which objectively measures the electrical activity of the photoreceptor cells in the retina) might detect a very mild form of RP.
A proband for pounds 2, from Proactive Health (see bums and tums).
It was also reported that the proband group had a higher rat e of academic problems, including suspension, drop out, expulsion, and having failed a grade.
A combination of low achievement and Verbal IQ-Achievement discrepancy criteria were employed, rather than low achievement only or Verbal IQ-Achievement discrepancy only, to determine whether a prospective proband qualified for the study and for the analyses based on categorical diagnoses reported in this article.
Where possible, archived DNA from family members was tested with PCR, restriction endonuclease (RE) or sequence analysis for the putative change identified in the proband.
In their clinical evaluation, it is important to know whether the proband was tested for multiple thrombophilic disorders, as presence of more than 1 defect is associated with higher VTE risk.
To facilitate the proband selection rates are set by the airport, which is at the expected passenger traffic to certain destinations and destination groups are based (about 60 target layers disproportionate approach).