Antibiotics Doxyrubicin 0 0 Mitomycin C + + + + + + Miscellaneous Dacarbazine + + Hydroxyurea 0 + Procarbazine
+ 0 Activity against indicated type of organism Antineoplastic Anaerobic Agent bacteria Yeasts Alkylating agents Carmustine 0 [+ or -] Chlorambecil + + Neoplatin ND 0 No activity shown by busulphan, cyclophosphamide, dibromomannitol, and melphalan.
Previous case reports have described treatment with vincristine, lomustine, and prednisone, (4) vincristine alone, (12) and procarbazine
, CCNU, and vincristine.
The patient was treated with five cycles of BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine
, prednisone) chemotherapy.
This changed after National Cancer Institute (NCI) researchers showed combining four drugs C mechlorethamine, vincristine (Oncovin), procarbazine
and prednisone, a regimen named MOPP C produced long-term remissions in more than 50 percent of adults with advanced Hodgkin lymphoma.
Title: Radiotherapy (RT), temozolomide (TMZ), procarbazine
(PCB), and the integrin inhibitor cilengitide in patients (pts) with glioblastoma (GBM) without methylation of the MGMT gene promoter (ExCentric): Results of an Australian phase II clinical trial.
Nine patients received Hodgkin lymphoma--type therapy, including five patients who received ABVD (doxorubicin, bleomycin, vinblastine, and dacarbazine), three patients who received CVPP (cyclophosphamide, vinblastine, procarbazine
, and prednisone), and one patient who received CVPP/ABVD.
Alkyl-ating chemotherapeutic agents, such as procarbazine
and/or cyclophosphamide, cause prolonged azoospermia in 90%-100H of men and premature ovarian failure (POP) in 5%-25% of younger women under 30 years old; however, the risks are low with radiotherapy alone if pelvic radiation or chemotherapy with alkylating agents is not given (22).
Treatment for Hodgkin's lymphoma with MVPP (mechlorethamine, vinblastine, procarbazine
and prednisolone), MOPP (mechlorethamine, vincristine, procarbazine
and prednisolone) or ChIVPP (chlorambucil, vinblastine, procarbazine
and prednisolone) resulted in permanent ovarian failure in 19 - 63% of cases.
Five of the patients who were diagnosed as Hodgkin lymphoma were treated with adriablastine, belomycine, vinblastine, dacabazine, six were treated with cyclophosphamide, oncovin, procarbazine
and prednisolone and six were treated with successive adriablastine, bleomycine, vinblastin, dacarbazine-cyclophosphmide, vincristin, procarbazine
The researchers compared various chemotherapy regimens and IFRT doses and found that outcomes were similar when 30 Gy of IFRT was combined with either four cycles of ABVD (doxorubicine, bleomycin, vinblastine, and dacarbazine) or four cycles of BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine
Plants have a long history of use in the treatment of cancer providing some of the currently used effective anticancer agents such as vinblastine, vincristine, mechlorethamine, prednisone, procarbazine
, etoposide, teniposide, paclitaxel, bleomycin, cisplatin and taxanes (DeVita et al.
2] Etoposide Dacarbazine 5-fluorouracil Mechlorethamine Gemcitabine Procarbazine
(oral) Methotrexate > 50 mg/ [m.