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A rare genetic disorder of childhood that is characterized by rapid onset of the physical changes typical of old age, usually resulting in death before the age of 20. Also called Hutchinson-Gilford progeria syndrome.

[pro- + Greek gēras, old age; see geriatrics + -ia.]


(Pathology) med premature old age, a rare condition occurring in children and characterized by small stature, absent or greying hair, wrinkled skin, and other signs of old age
[C20: from pro-2 + Greek gēras old age]


(proʊˈdʒɪər i ə)

a rare congenital abnormality characterized by premature and rapid aging, the affected individual appearing in childhood as an aged person.
[1900–05; < Greek progḗr(ōs) prematurely old (pro- pro-2 + -gēros, adj. derivative of gêras old age) + -ia]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.progeria - a rare abnormality marked by premature aging (grey hair and wrinkled skin and stooped posture) in a child
abnormalcy, abnormality - an abnormal physical condition resulting from defective genes or developmental deficiencies


n progeria
References in periodicals archive ?
Lucy, who was eight and from Ballyward, Co Down, was diagnosed with Hutchinson Gilford Progeria Syndrome - more commonly known as Progeria - shortly after birth.
The 17-year-old boy, Sam Berns, who became the face of progeria, also famously called the "Benjamin Button" disease, died in 2014 from complications of the disease.
In the research, Yamanaka factors were induced for a short period of time in the skin cells of mice with the aging disease progeria.
Tenders are invited for seeking proposals for research projects in all areas directly relevant to progeria.
The accumulating evidence for accelerated aging in schizophrenia has promoted some researchers to consider it a form of progeria (12) because of the accelerated aging features that patients with schizophrenia manifest.
That could have been a make believe tale, yet there is this extremely unusual pathology known as Progeria or the Hutchinson-Gilford Progeria Syndrome 3 where children remove to look ancient even before they're two years of ages, without disturbance in intellectual development or motor ability advancement.
The findings also show promise in counteracting premature aging disorders such as Hutchinson-Gilford progeria syndrome.
The findings, published June 29 in the journal Stem Cells, also show promise in counteracting premature aging disorders such as Hutchinson-Gilford progeria syndrome.
Progeria patients have mutations in genes responsible for DNA damage repair.
Better views will also help scientists understand the role that disrupted nucleomes play in aging and diseases, such as progeria and cancer.
The teenager who won the nation's hearts while suffering from rare premature ageing disorder progeria, which gave her the body of 104-year-old, died on Thursday.