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Related to progestin: progesterone


Any of several synthetic progestational substances that mimic some or all of the actions of progesterone, used as contraceptives either alone or in combination with estrogen, and with estrogen in hormone replacement therapy.


(proʊˈdʒɛs tɪn)

also pro•ges•to•gen

(-ˈdʒɛs tə dʒən)

any substance having progesteronelike activity.
[1925–30; pro-1 + gest (ation) + -in1]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.progestin - any of a group of steroid hormones that have the effect of progesterone
sex hormone, steroid hormone, steroid - any hormone affecting the development and growth of sex organs
Lipo-Lutin, progesterone - a steroid hormone (trade name Lipo-Lutin) produced in the ovary; prepares and maintains the uterus for pregnancy
megestrol, megestrol acetate - a synthetic progestational compound used to treat endometrial carcinoma
norethandrolone, norethindrone, norethindrone acetate, Norlutin - a synthetic progestational hormone (trade name Norlutin) used in oral contraceptives and to treat endometriosis
norethynodrel - a progesterone derivative used in oral contraceptives and in the control of menstruation and the treatment of abnormal uterine bleeding
norgestrel - synthetic progestin used in oral contraceptives
medroxyprogesterone, Provera - a progestin compound (trade name Provera) used to treat menstrual disorders
References in periodicals archive ?
CombiPatch delivers the estrogen 17-beta-estradiol and the progestin norethindrone acetate (NETA) through a state-of-the-art "matrix" patch technology that releases the two hormones from the patch's adhesive.
The new estrogen results come a day after an encouraging report from Brigham and Women's Hospital in Boston, which said post-menopausal women may ward off heart disease as effectively with a commonly prescribed combination of estrogen and progestin as with straight estrogen.
The study aims to provide greater insight into the genetic contribution to these three chronic diseases, each a major cause of death, disability and frailty among postmenopausal women of all races and socioeconomic backgrounds, and to relate these findings to the effects of estrogen plus progestin (E+P) therapy.
Washington, Mar 4 (ANI): Women aged 50 to 76 who use hormone replacement therapy combining estrogen and progestin may have a higher risk of lung cancer than non-users, a new study has found.
Recent studies originating from both the USA and Europe suggest that the combined treatment regimens with estrogen and progestin increase the risk of breast cancer beyond the risk following the use of unopposed estrogen.
However, in keeping with many of the other risks reported with estrogen plus progestin therapy, there was speculation that the progestin component was responsible for the increased risk.
Organon Laboratories' Implanon, a three-year, single-rod system that releases the progestin etonorgestrel, has been approved for use in the United Kingdom.
First, progestin is not medroxyprogesterone acetate.
A related study from 2002 linked a therapy combining estrogen and progestin with increased risks of breast cancer, heart attack and stroke.
Women in menopause who have symptoms are currently treated with a combination of estrogen plus progestin hormone therapy, however this treatment comes with side effects, including a higher risk of breast cancer caused by the progestin.
Potential adverse effects of long-term use of progestin with estrogen include invasive breast cancer, heart disease-related events, dementia, including Alzheimer's disease, stroke and blood clots.

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