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scleroderma
(redirected from progressive systemic sclerosis)

   Also found in: Medical, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
scle·ro·der·ma  (sklîr-dûrm)
n.
A pathological thickening and hardening of the skin.

scleroderma [ˌsklɪərəʊˈdɜːmə], sclerodermia [ˌsklɪərəʊˈdɜːmɪə], scleriasis [sklɪˈraɪəsɪs]
n
(Medicine / Pathology) a chronic progressive disease most common among women, characterized by a local or diffuse thickening and hardening of the skin
[from New Latin sclerōdermus, from Greek, from sklēros hard + derma skin]

scleroderma  (sklîr-dûrm)
A connective tissue disease characterized by the deposition of fibrous tissue into the skin and often other organs, causing tissue hardening and thickening.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.scleroderma - an autoimmune disease that affects the blood vessels and connective tissuescleroderma - an autoimmune disease that affects the blood vessels and connective tissue; fibrous connective tissue is deposited in the skin
autoimmune disease, autoimmune disorder - any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues
morphea - localized scleroderma
2.Scleroderma - genus of poisonous fungi having hard-skinned fruiting bodies: false truffles
fungus genus - includes lichen genera
family Sclerodermataceae, Sclerodermataceae - a family of fungi or order Sclerodermatales with a single-layered peridium; includes earthballs
earthball, hard-skinned puffball, puffball, false truffle - any of various fungi of the genus Scleroderma having hard-skinned subterranean fruiting bodies resembling truffles
Scleroderma aurantium, Scleroderma citrinum - an earthball fungus that is a dingy brownish yellow and a dark purplish interior; the peridium is covered with a pattern of small warts
Scleroderma flavidium, star earthball - an earthball with a smooth upper surface that is at first buried in sand; the top of the fruiting body opens up to form segments like the ray of an umbel
Scleroderma bovista, smooth earthball - an earthball with a peridium that is firm dry and smooth when young but developing cracks when mature; pale orange-yellow when young and reddish brown at maturity


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8) Progressive systemic sclerosis (PSS) or scleroderma is a disorder of connective tissue, vascular lesions are prominent in PSS and are responsible for many pathological changes.
1,2) Anti-ENA titers are used for the diagnosis of systemic lupus erythematosus (SLE), neonatal lupus, Sjogren syndrome (SS), mixed connective tissue disease (MCTD), polymyositis/dermatomyositis (PM/DM), and progressive systemic sclerosis (PSS), with variable sensitivity and specificity.
 
 
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