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proinsulin

   Also found in: Medical, Wikipedia 0.01 sec.
pro·in·su·lin  (pr-ns-ln)
n.
A single-chain polypeptide that is the precursor of insulin, converted into insulin by enzymatic action.


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Missing ClC-3 therefore appears to cause a dramatic slowdown of the conversion of proinsulin to insulin.
The method involves delivering into the subject a genetic construct comprising a coding sequence for a human proinsulin operably connected a promoter functional in the host cells.
You consider clozapine, but the patient has an elevated body mass index with central obesity, an elevated proinsulin level, and a hemoglobin [A.
 
 
 
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