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protease

   Also found in: Medical, Encyclopedia, Wikipedia 0.01 sec.
pro·te·ase  (prt-s, -z)
n.
Any of various enzymes, including the endopeptidases and exopeptidases, that catalyze the hydrolytic breakdown of proteins into peptides or amino acids.

protease [ˈprəʊtɪˌeɪs]
n
(Life Sciences & Allied Applications / Biochemistry) any enzyme involved in proteolysis
[from protein + -ase]

protease  (prt-s)
Any of various enzymes that bring about the breakdown of proteins into peptides or amino acids by hydrolysis. Pepsin is an example of a protease.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.protease - any enzyme that catalyzes the splitting of proteins into smaller peptide fractions and amino acids by a process known as proteolysis
caspase - any of a group of proteases that mediate apoptosis
enzyme - any of several complex proteins that are produced by cells and act as catalysts in specific biochemical reactions
angiotensin converting enzyme, angiotensin-converting enzyme, ACE - proteolytic enzyme that converts angiotensin I into angiotensin II
plasminogen activator, urokinase - protease produced in the kidney that converts plasminogen to plasmin and so initiates fibrinolysis
renin - a proteolytic enzyme secreted by the kidneys; catalyzes the formation of angiotensin and thus affects blood pressure


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Byline: ANI Washington, Sep 7 (ANI): By using protease inhibitors, researchers at the University of California-San Francisco (UCSF) have restored to normal levels a key protein that is involved in early brain development, and causes the rare brain disorder lissencephaly.
DiscoveRx Corporation (Fremont, CA) has patented methods and reagents for measuring protease activity.
In the first agreement, Medivir has outlicensed its preclinical human immunodeficiency virus (HIV) protease inhibitor project and in the second agreement provided a license for the MIV-210 polymerase inhibitor compound for HIV and hepatitis B (HBV).
 
 
 
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