prothrombin


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pro·throm·bin

 (prō-thrŏm′bĭn)
n.
A plasma protein that is converted into thrombin during blood clotting.

prothrombin

(prəʊˈθrɒmbɪn)
n
(Biochemistry) biochem a zymogen found in blood that gives rise to thrombin on activation. See also phylloquinone

pro•throm•bin

(proʊˈθrɒm bɪn)

n.
a plasma protein involved in blood coagulation that is converted to thrombin.
[1895–1900]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.prothrombin - a protein in blood plasma that is the inactive precursor of thrombin
clotting factor, coagulation factor - any of the factors in the blood whose actions are essential for blood coagulation
Translations

pro·throm·bin

n. protrombina, una de las cuatro proteínas principales del plasma junto a la albúmina, la globulina y el fibrinógeno.
References in periodicals archive ?
Objective: To determine the frequency of prothrombin gene mutation in venous thromboembolism in our population.
Contract award notice: Concentrate of activated prothrombin syndrome (apcc) with delivery to the national blood center deposit warehouse.
However, the patient was found to have a heterozygous prothrombin G20210A (factor II) mutation.
Ganzert et al [4] retrospectively analysed the outcome of a large series of amatoxin intoxication cases and found that predictors of death were the prothrombin time in combination with the serum creatinine level on 3-10 days after ingestion.
It is known that mutations in the prothrombin gene are a risk factor for thrombosis.
Research variables were AST/ALT ratio, prothrombin time, platelet conunt, serum albumin and serum bilirubin.
For this study, published in Arteriosclerosis, Thrombosis, and Vascular Biology, researchers determined VKDP activity by measuring circulating des-[gamma]-carboxy prothrombin concentrations in a random sample of 709 multiethnic adults free of cardiovascular disease drawn from the Multi-Ethnic Study of Atherosclerosis (MESA).
Anonactivated, 4-factor prothrombin complex concentrate (4F-PCC) known as Kcentra (CSL Behring, Kankakee, Illinois) has been approved in the United States for the reversal of vitamin K antagonist (VKA) anticoagulation in patients with major acute hemorrhage, or in patients who require urgent surgical intervention.
Coagulation studies at that time showed a prolonged prothrombin time of 18 seconds {normal 11.
M2 EQUITYBITES-October 21, 2014-China Biologic Products receives approval for manufacturing of human prothrombin complex concentrate at Shandong Taibang facility
M2 PHARMA-October 21, 2014-China Biologic Products receives approval for manufacturing of human prothrombin complex concentrate at Shandong Taibang facility
The prothrombin time (PT) and the activated partial thromboplastin time (APTT) are global coagulation tests used to assess the coagulation system in a clinical setting.