proton-pump inhibitor


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proton-pump inhibitor

n
(Pharmacology) any of a group of drugs used to treat excessive secretion of acid in the stomach and any resulting ulcers. They block the enzyme (proton pump) in the cells of the gastric glands that secrete hydrochloric acid
References in periodicals archive ?
Systematic review: proton-pump inhibitor failure in gastro-oesophageal reflux disease--where next?
Q I have gastroesophageal reflux disease (GERD), and take an over-the-counter H2 blocker to ease my heartburn--but would a proton-pump inhibitor be more effective?
For the study, researchers at RTI International, University of Michigan, and University of North Carolina at Chapel Hill used a Markov model to compare the costs and outcomes of prescribing low-dose aspirin alone, aspirin plus a proton-pump inhibitor, or no treatment for coronary heart prevention.
Several months earlier, his primary care physician had started him on a proton-pump inhibitor twice daily.
Some falls could be attributed to dizziness caused by a proton-pump inhibitor (PPI).
5%) had concomitant use of a proton-pump inhibitor or misoprostol.
On April 29, 2005 GlaxoSmithKline announced that a drug-interaction trial of Lexiva (fosamprenavir) with Nexium (esomeprazole, a proton-pump inhibitor, often used to reduce stomach acidity for relief of reflux, the unwanted flow of stomach acid into the esophagus), had found no reduction in the in the blood level of amprenavir.
Rather than clopidogrel, aspirin plus a proton-pump inhibitor should be prescribed to prevent recurrent bleeding from ulcers in high-risk patients, according to results of a double-blind, randomized trial.
Risk of community-acquired pneumonia with outpatient proton-pump inhibitor therapy: a systematic review and meta-analysis.
He also had had laryngopharyngeal reflux for several years, for which he had been treated with a proton-pump inhibitor twice daily.
A new study has found that if Reyataz (atazanavir), whether taken with or without ritonavir, is used with Prilosec (omeprazole, a proton-pump inhibitor used to reduce stomach acidity, for treating acid-reflux disease or other conditions), the blood level of atazanavir is reduced by three quarters or more, probably making it ineffective and leading to viral resistance.
The proton-pump inhibitor lansoprazole enhances amyloid beta production.