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Related to protopathic: protopathic sensibility, Protopathic Pain


Sensing pain, pressure, heat, or cold in a nonspecific manner, usually without localizing the stimulus. Used especially of certain sensory nerves.

[From Medieval Greek prōtopathēs, affected first, from Greek prōtopathein, to feel first : prōto-, proto- + pathos, experience, feeling.]

pro·top′a·thy (-tŏp′ə-thē) n.


1. (Physiology) of or relating to a sensory nerve that perceives only coarse stimuli, such as pain
2. (Physiology) of or relating to such perception
[C20: from proto- + Greek pathos suffering, disease + -ic]
protopathy n


(ˌproʊ təˈpæθ ɪk)

of or pertaining to neurons that sense only general areas of pain, heat, or cold.
pro•top•a•thy (prəˈtɒp ə θi) n.
References in periodicals archive ?
I reported the data because they are very dramatic, but the question remains, is it a protopathic effect?
To avoid the possibility of protopathic bias, we excluded antimicrobial drug prescriptions made during the 29 days prior to the index date.
To reduce the risk for protopathic bias (8), we did a sensitivity analysis in which we considered any patient /// who had a recent (90-day) diagnosis of infectious diarrhea to be unexposed to fluoroquinolones.