protoporphyrin


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Related to protoporphyrin: Zinc Protoporphyrin

pro·to·por·phy·rin

 (prō′tō-pôr′fə-rĭn)
n.
A metal-free porphyrin, C34H34N4O4, that combines with ferrous iron to form the heme group in hemoglobin and myoglobin, and with ferric iron to form the hemin group in catalase and some cytochromes.

protoporphyrin

(ˌprəʊtəʊˈpɔːfɪrɪn)
n
(Biochemistry) a type of porphyrin that, when combined with an iron atom, forms haem, the oxygen-bearing prosthetic group of the red blood pigment haemoglobin
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References in periodicals archive ?
The bone marrow no longer has sideroblasts, and there is not enough iron to put in the heme protoporphyrin ring.
A separate study of 12 healthy adults found that pretreatment with an ablative fractional laser significantly intensifies protoporphyrin IX fluorescence to a larger extent than curettage, microdermabrasion, microneedling, and nonablative fractional laser (JAMA Derm.
The two pigments found in the eggshells were protoporphyrin and biliverdin.
Any genetic defects that impact this process can interrupt the body's ability to produce heme; the decreased heme production leads to a buildup of protoporphyrin components.
Thus more protoporphyrin is formed which is incorporated into the hemoglobin molecule in place of heme.
Cystatin-C, zinc protoporphyrin, urine creatinine clearance testing, ASO antibody titers, anti-DNAase antibody titers, microsomal antibodies, urine microalbumin, urine cultures for crystals and bacterial burdens, for example, are useful in uncovering suspected renal impairment.
In a condition such as IBD, further analyses may be required to confirm IDA, such as reticulocyte hemoglobin content, percentage of hypochromic red blood cells, transferrin saturation index, and zinc protoporphyrin, but these tests are not yet widely available (Table 3).
Addition of a metal atom to the central portion of protoporphyrin results in the formation of an organic prosthetic group.
Indicators of the iron status of populations: free erythrocyte protoporphyrin and zinc protoporphyrin; serum and plasma iron, total iron binding capacity and transferrin saturation; and serum transferrin receptor.
Serum protoporphyrin levels, plasma hepcidin and transferrin receptor saturation assay14 are alternative tests.
Under the method, an optical fibre probe is used on the inside of the lip to detect the faint fluorescence of red blood cell zinc protoporphyrin, a compound found in red blood cells when heme production is inhibited by lead or by a lack of iron.