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protoporphyrin

   Also found in: Medical, Wikipedia 0.01 sec.
pro·to·por·phy·rin  (prt-pôrf-rn)
n.
A metal-free porphyrin, C32H32N4(COOH)2, that combines with ferrous iron to form the heme group in hemoglobin and myoglobin, and with ferric iron to form the hemin group in catalase and some cytochromes.
protoporphyrin [ˌprəʊtəʊˈpɔːfɪrɪn]
n
(Life Sciences & Allied Applications / Biochemistry) a type of porphyrin that, when combined with an iron atom, forms haem, the oxygen-bearing prosthetic group of the red blood pigment haemoglobin
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When blood lead is high, an increase in erythrocyte protoporphyrin (EP) follows.
Blood metal analysis to biomonitor and diagnose acute vs. chronic ... by Blaurock-Busch, E. / Townsend Letter
Associations of delta-aminolevulinic acid dehydratase genotype with plant, exposure duration, and blood lead and zinc protoporphyrin levels in Korean lead workers.
The epidemiology of lead toxicity in adults: measuring dose and ... by Schwartz, Brian S. / Environmental Health Perspectives
A Centers for Disease Control and Prevention (CDC) statement issued in 1991 lowering the blood-lead concentration level deemed harmful to children had the dual effect of 1) rendering the erythrocyte protoporphyrin test unsuitable for lead-screening purposes because of poor specificity and sensitivity, and 2) challenging laboratories to use a direct test for measuring blood-lead concentration that would produce accurate results, both for screening and diagnostic purposes.
Interlaboratory surveys to assess performance: more than proficiency ... by Hassemer, David J. / Medical Laboratory Observer
 
 
 
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