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provirus
(redirected from proviruses)

   Also found in: Medical, Encyclopedia, Wikipedia 0.02 sec.
pro·vi·rus  (prvrs, pr-v-)
n. pl. pro·vi·rus·es
The precursor or latent form of a virus that is capable of being integrated into the genetic material of a host cell and being replicated with it.

proviral (-rl) adj.

provirus [ˈprəʊˌvaɪrəs]
n
(Medicine / Pathology) the inactive form of a virus in a host cell
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.provirus - cDNA copy of the RNA genome of a retrovirus; the genetic material of a virus as incorporated into and able to replicate with the genome of a host cell
cDNA, complementary DNA - single-stranded DNA that is complementary to messenger RNA or DNA that has been synthesized from messenger RNA by reverse transcriptase


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Scientists from Tokyo-based Nihon University highlight the fact that latently infected cells harbour HIV-1 proviral DNA genomes integrated with heterochromatins, allowing for the persistence of transcriptionally silent proviruses.
The alternate, more sophisticated, and more "down the road" approach is to use molecular probes that seek, find, and destroy cells harboring HIV genomes--even those hidden in the cell as silent DNA proviruses.
Molecular epidemiologic studies have shown HTLV-1 proviruses to be remarkably stable genetically.
 
 
 
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