pyrogenicity


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py·ro·gen·ic

 (pī′rō-jĕn′ĭk) also py·rog·e·nous (pī-rŏj′ə-nəs)
adj.
1. Producing or produced by fever.
2. Caused by or generating heat.
3. Of or relating to solid rock formed from molten rock; igneous.

py′ro·ge·nic′i·ty (-rō-jə-nĭs′ĭ-tē) n.

pyrogenicity

(ˌpaɪrəʊdʒəˈnɪsɪtɪ)
n
(Medicine) med the characteristic of causing fever
References in periodicals archive ?
One of the most successful alternative methods, the Limulus assay, has replaced about 90% of pyrogenicity testing.
Earlier in 2017, the company received long-term implantation results from parts 3, 10, 6 and 11 of the ISO 10993 (Biological Evaluation of Medical Devices) suite of tests, which include evaluation of genotoxicity, sub-chronic systemic toxicity and pyrogenicity.
A few examples of such processes are: acid treatment and microwave radiation, resulting in a reduction from 10 to 3 kDa, but with the disadvantage of high cost and residual acidity [33] ; irradiation at different temperatures in acid medium for 35 days to achieve a reduction from 71 to 21 kDa [10]; and enzymatic reactions using proteases such as papain, a cysteine protease, keeping in mind, however, that a high level of pyrogenicity may occur due to the presence of proteins mixed with the end product [8], as the focus of application is biomedical.
Included are cytotoxicity, sensitization, intracutaneous reactivity, acute systemic toxicity, implantation (two, 12, and 26 weeks), hemocompatibility (hemolysis and PPT), and pyrogenicity.
Pyrogenicity tests: Implants, as well as sterile devices, should meet pyrogen limit specifications.
Among his topics are pyrogenicity and bacterial endotoxin, electron beam processing, hydrogen peroxide vapor sterilization, cleaning and disinfecting sterile processing facilities, and auditing sterilization processes and facilities.
62,63) In addition, it should be monitored for sterility and pyrogenicity.
For ISO 10993 evaluation, materials are assessed for cytotoxicity, pyrogenicity and sensitization.