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Related to quetiapine: quetiapine fumarate


An antipsychotic drug, C21H25N3O2S, that acts as an antagonist of multiple neurotransmitters including serotonin and norepinephrine and is used in its fumarate form to treat schizophrenia and bipolar disorder.

[que-, origin unknown + t(h)ia(ze)pine, one of its chemical constituents (thi(o)- + az(o)- + ep(oxide) + -ine).]


n quetiapina
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Developed by AstraZeneca plc, quetiapine (under the trade name of Seroquel) is an important drug for the treatment of schizophrenia.
In his past medical history he was treated with lithium 1200 mg/day quetiapine 200 mg/day and olanzapine 20 mg/day because of an exaggerated sense of self confidence believing that he was a wealthy person, excessive money spending, insomnia, feeling full of energy and quarrelling with others for the last five months.
By randomly assigning the study's 482 participating outpatient adults to either lithium or quetiapine, while allowing clinicians to prescribe adjunctive treatment as necessary; and by using a broader-than-usual set of inclusion criteria, the investigators hoped to provide clinicians with "real-world" data on how the respective mood stabilizers perform.
Olanzapine, risperidone, and quetiapine are associated with a higher risk of weight gain, and aripiprazole and ziprasidone have been linked to a higher risk of extrapyramidal side effects.
The Quetiapine level was "considerably higher than for therapeutic use".
The experts concluded: "The data suggest that the risk of mortality with these drugs is generally increased with higher doses and seems to be highest for haloperidol and least for quetiapine.
Patients taking olanzapine showed an increase in low-density lipoprotein-cholesterol (LDL-C) levels, and those taking either olanzapine or quetiapine had higher triglyceride levels.
Patients on olanzapine showed increased LDL cholesterol, and patients on olanzapine or quetiapine had higher triglycerides.
Dr Amin said:" Quetiapine Sustained Release from AstraZeneca enhances compliance.
Cocaine users take sedative Quetiapine to deal with withdrawal symptoms.
The spectrum of toxicity for both baclofen and quetiapine in overdose has been previously described.
There will be a limited run of 50 CDs of Quetiapine at the Georgian Theatre gig, backed by old favourite Spill Over and will cost pounds 1.