quinacrine


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Related to quinacrine: mepacrine

quin·a·crine

 (kwĭn′ə-krēn′)
n.
A compound, C23H30ClN3O, administered in its hydrochloride form, that was formerly used as an antimalarial and antihelminthic drug and, in some countries, has been used as an agent for the nonsurgical sterilization of women.

quinacrine

(ˈkwɪnəˌkriːn)
n
1. (Pharmacology) another name for mepacrine
2. (Medicine) quinacrine mustard a nitrogen mustard derived from mepacrine and used as a stain for chromosomes
[C20: from quin(ine) + acr(id) + -ine2]

quin•a•crine

(ˈkwɪn əˌkrin)

n.
an alkaloid, C23H30ClN3O, used in the treatment of malaria.
[1930–35; quin (ine) + acr (id) + -ine2]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.quinacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malariaquinacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria
antimalarial, antimalarial drug - a medicinal drug used to prevent or treat malaria
anthelminthic, anthelmintic, helminthic, vermifuge - a medication capable of causing the evacuation of parasitic intestinal worms
Translations

quinacrine

n quinacrina, mepacrina (INN)
References in periodicals archive ?
Croft, Antiprotozoal and cytotoxicity evaluation of sulfonamide and urea analogues of quinacrine, Med.
Quinacrine was used as add-on therapy by 21% of dermatologists and 15% of rheumatologists.
Letter: A new consistent chromosomal abnormality in chronic my elogenous leukemia identified by quinacrine fluorescence and Giemsa staining.
For example, quinacrine is a fluorescent acridine derivative that stains peptide-bound ATP found in high concentrations in intracellular granules (Irvin and Irvin, 1954: Bodin and Burnstock, 2001).
One case received quinacrine following treatment failure of metronidazole.
For example, one compound, quinacrine (Atabrine), was effective against malaria, albeit with nasty side effects, like turning the skin bright yellow.
9) Another treatment option is quinacrine HC1, which has been used for treatment of Atoxoplasma and Plasmodium, at 5-10 mg/kg PO q24h for 7-10 days; however, chloroquine and primaquine are preferred, as overdose of quinacrine HC1 can cause hepatotoxicity.
quinacrine staining for male cells) (6, 7) methods.
Volunteers provided free quinine and quinacrine tablets every 7 days to febrile citizens (1,2).
A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining.
Quinacrine is not approved for sterilization in the United States.