quinacrine


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Related to quinacrine: mepacrine

quin·a·crine

 (kwĭn′ə-krēn′)
n.
A compound, C23H30ClN3O, administered in its hydrochloride form, that was formerly used as an antimalarial and antihelminthic drug and, in some countries, has been used as an agent for the nonsurgical sterilization of women.

quinacrine

(ˈkwɪnəˌkriːn)
n
1. (Pharmacology) another name for mepacrine
2. (Medicine) quinacrine mustard a nitrogen mustard derived from mepacrine and used as a stain for chromosomes
[C20: from quin(ine) + acr(id) + -ine2]

quin•a•crine

(ˈkwɪn əˌkrin)

n.
an alkaloid, C23H30ClN3O, used in the treatment of malaria.
[1930–35; quin (ine) + acr (id) + -ine2]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.quinacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malariaquinacrine - a drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria
antimalarial, antimalarial drug - a medicinal drug used to prevent or treat malaria
anthelminthic, anthelmintic, helminthic, vermifuge - a medication capable of causing the evacuation of parasitic intestinal worms
Translations

quinacrine

n quinacrina, mepacrina (INN)
References in periodicals archive ?
Volunteers provided free quinine and quinacrine tablets every 7 days to febrile citizens (1,2).
A new consistent chromosomal abnormality in chronic myelogenous leukaemia identified by quinacrine fluorescence and Giemsa staining.
Reactive oxygen species generation by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine.
Standard of care currently includes sun avoidance, topical as wells as intralesional steroids, antimalarials, including combining hydroxychloroquine or chloroquine with quinacrine, monitoring with cutaneous lupus disease area and severity index (CLASI) to allow for standardized assessment of skins disease activity and damage, low dose oral steroids, as well as MTX, AZA, MMF and belimumab.
Curaxins include CBL0137, which is a carbazole and CBL0102, which is a quinacrine.
14] verified the effect of various anti-inflammatory agents as retinoic acid, quinacrine and dipyridamole in reducing adhesions in animals.
When quinacrine was added to the treatment regimen of the nonresponders, two-thirds experienced a lessening of their disease.
Rowley JD: Identification of a translocation with quinacrine fluorescence in a patient with acute leukemia.
Reactive oxygen species generated by human spermatozoa is induced by exogenous NADPH and inhibited by the flavoprotein inhibitors diphenylene iodonium and quinacrine.
Quinacrine sterilization for human immunodeficiency virus-positive women, Fertility and Sterility, 2009, 92(1):108-115.
Safety and efficacy of quinacrine in human prion disease (RION-1 study): a patient preference trial.
The reduction of serum B-lymphocyte activating levels following quinacrine add-on therapy in systemic lupus erythe matosus.