(redirected from Quinolines)
Also found in: Medical, Encyclopedia.


 (kwĭn′ə-lēn′, -lĭn)
An aromatic organic base, C9H7N, having a pungent tarlike odor, synthesized or obtained from coal tar, and used as a food preservative and in making antiseptics, drugs, and dyes.


(ˈkwɪnəˌliːn; -lɪn)
1. (Elements & Compounds) an oily colourless insoluble basic heterocyclic compound synthesized by heating aniline, nitrobenzene, glycerol, and sulphuric acid: used as a food preservative and in the manufacture of dyes and antiseptics. Formula: C9H7N
2. (Elements & Compounds) any substituted derivative of quinoline


(ˈkwɪn lˌin, -ɪn)

a colorless liquid nitrogenous base, C9H7N, having a disagreeable odor, occurring in coal tar: used as a solvent and reagent and to make dyes.
References in periodicals archive ?
The same result was observed for quinolines, an antifolate, or atovaquone (Table 1).
Efficacy of orally administered 2-substituted quinolines in experimental murine cutaneous and visceral leishmaniases.
The nitrogen in the feedstock has three characteristics: 1) the N content of nitriles is high, 2) the content of basic nitrogen (anilines, pyridines, quinolines and acridines) is about 29 wt%, and 3) the nonbasic nitrogen content is lower than that in general shale oils.
Topics covered include ring synthesis, substituent installation and modification, reduction to partially hydrogenated pyridines, piperidines, and quinolines, alkaloid synthesis, fluorination, and the use of pyridines as reagents.
On the other hand quinolines exhibit antimalarial [12], antiplasmodial [13], antiproliferative [14], antibacterial [15], antifungal [15].
Though halogenated quinolines have been used for a long time, information on their metabolism is scarce.
In a potential breakthrough, Oregon researchers have developed new drugs that not only kill malaria parasites, but also restore the effectiveness of a generation of inexpensive drugs call quinolines, to which parasites have become resistant.
In vivo efficacy of oral and intra-lesional administration of 2-substituted quinolines in experimental treatment of new world cutaneous Leishmaniasis caused by Leishmania amazonensis.
Quinolines and dithiocarbamates find use in specialized applications.
According to a report of the work in the November-December JOURNAL OF FOOD SCIENCE, all fibers bound at least 8 percent of the quinolines, and some bound as much as 22 percent, depending on the fiber and the particular quinoline.
Again, some polycyclic aromatic nitrogen hydrocarbons (PANH) present in the aromatic fraction of shale oil, such as quinolines and methylquinolines, are extremely harmful to human health due to their toxicity, mutagenicity and carcinogenicity [15, 16].