quinolone


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quin·o·lone

 (kwĭn′ə-lōn′)
n.
Any of a class of synthetic broad-spectrum antibacterial drugs derived from quinoline compounds.

quinolone

(ˈkwɪnəˌləʊn)
n
1. (Pharmacology) any of a group of synthetic antibiotics, including ciprofloxacin, that inactivate an enzyme required for the replication of certain microorganisms
2. (Pathology) any of a group of synthetic antibiotics, including ciprofloxacin, that inactivate an enzyme required for the replication of certain microorganisms
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References in periodicals archive ?
Public hearing to be organised for quinolone and fluoroquinolone antibiotics
Regarding to the research of quinolones and sulfonamides, among 99 samples were analyzed, being four of them positive for quinolone group, and six samples showed positive results for sulfonamides residues (Table 1).
The effect on the viscosity and ash content of the coal tar were investigated by altering temperature, time, and the amount of quinolone and Zn(OH)2.
Researchers made the unexpected finding that bacteria that mutated to become resistant to quinolone antibiotics also became more resistant to triclosan.
These isolates were also subjected to susceptibility testing and polymerase chain reaction for four groups of genes including int encoding integron elements, sull and sulll encoding trimethoprim-sulfamethoxazole resistance and smqnr encoding quinolone resistance.
The first quinolone (quinoJ[ine] + -one [compound related to ketone]), nalidixic acid, was isolated as a byproduct of chloroquine (see "quinine," https://wwwnc.
doxycycline orally, 40 mg/kg every 12 h for 14 days; and quinolone orally, 40 mg/ kg/day of body weight for 14 days).
Key Words: Prostate biopsy, infection, sepsis, quinolone resistance, ciprofloxacin.
Quinolone resistance in Enterobacteriaceae usually originates from mutations in target enzymes (DNA gyrase and/or topoisomerase IV) or because of impaired access to the target, occurring either because of changes in porin expression or because of over expression of efflux pumps.
5-7) In four out of six randomized, controlled trials, ofloxacin was the quinolone used in combination with rifampin.
Resistance mechanisms such as production of [beta]-lactamases, plasmid-mediated quinolone resistance (PMQR) and carbapanemases have caused serious therapeutic problems.
There is not so much information about the recent status of quinolone resistant E.