Important causes of lower back pain Mechanical Neurological Systemic Disc herniation Radiculopathy
Inflammatory spondyloarthropathy Spinal canal Myelopathy Metabolic stenosis bone diseases Disc and segmental Neuropathy Neoplasia, degradation, e.
Lpath's preclinical studies showed strong in vivo results with Lpathomab in several different pain models, which suggest that LPA may be an attractive target across a variety of chronic pain conditions, including diabetic peripheral neuropathy, post-herpetic neuralgia, chemotherapy-induced neuropathic pain and pain associated with lumbosacral radiculopathy
Exam and history were consistent with lumbar radiculopathy
Its DTRAX platform of cervical devices are used to provide indirect decompression and fusion in patients suffering from cervical radiculopathy
secondary to degenerative disc disease.
Two subjects underwent revision for immediate postoperative radiculopathy
due to implant malposition.
2,7) Stage one presents with focal back pain in the affected area (predominant symptom); stage two presents as radiculopathy
at the level of the affected area; stage three presents as motor weakness, sensory deficit, and loss of bowel and bladder control; finally stage four presents with paralysis.
Clinically, research suggests that PEME may have benefit for ankle injury (Pennington et al 1993), neck pain or acute whiplash (Foley-Nolan et al 1990, Foley-Nolan et al 1992), osteoarthritis (Ay and Evcik 2009, Pipitone and Scott 2001, Trock et al 1994), LBP (Harden et al 2007) and lumbar radiculopathy
(Omar et al 2012).
The Natural History Of Herniated Nucleus Pulposus With Radiculopathy
Additionally, CNV1014802 has demonstrated proof of concept for treating pain associated with lumbosacral radiculopathy
, more commonly known as sciatica, and has potential applicability in several other neuropathic pain states.
Her main complaint from the onset, together with absence of weakness of ankle movements despite the presence of the same symptom as in 2003, absence of any evidence of pyramidal symptoms on examination, or absence of radiological features of myelopathy or radiculopathy
, strongly suggests presentation with leg apraxia at onset.
A case of cervical radiation radiculopathy
resembling motor neuron disease.
After 4-6 weeks, patients with persistent LBP or signs of radiculopathy
or spinal stenosis should be evaluated with magnetic resonance imaging (MRI) or computed tomography (CT) only if they are expected to benefit from invasive treatments, such as surgery or epidural steroid injection (Chou et al.