radioimmunoassay

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ra·di·o·im·mu·no·as·say

 (rā′dē-ō-ĭm′yə-nō-ăs′ā, -ĭm-yo͞o′-)
n. Abbr. RIA
A technique used to quantitate minute amounts of a substance, such as a hormone, in blood or another liquid. It involves the use of radioisotopes and of antibodies to the substance being investigated.

radioimmunoassay

(ˈreɪdɪəʊˌɪmjʊnəʊˈæseɪ)
n
(Medicine) a sensitive immunological assay, making use of antibodies and radioactive labelling, for the detection and quantification of biologically important substances, such as hormone concentrations in the blood

ra•di•o•im•mu•no•as•say

(ˌreɪ di oʊˌɪm yə noʊˈæs eɪ, -æˈseɪ, -ɪˌmyu-)

n.
a test procedure that integrates immunologic and radiolabeling techniques to measure minute quantities of a substance, as a drug, in a given sample of body fluid or tissue.
[1960–65]
ThesaurusAntonymsRelated WordsSynonymsLegend:
Noun1.radioimmunoassay - immunoassay of a substance that has been radioactively labeled
immunoassay, immunochemical assay - identification of a substance (especially a protein) by its action as an antigen; "PSA in the blood can be measured with an immunochemical assay"
Translations

ra·di·o·im·mu·no·as·say

n. radioinmunoensayo, prueba para determinar la concentración de suero de proteína como una reacción a la injección de una sustancia radioactiva.
References in periodicals archive ?
Tenders are invited for Supply of technetium generator kits for scintigraphic studies and kits for radioimmunoassays of tumor markers in applied specification
8 October 2013 - French in-vitro diagnostics and drug discovery company Cisbio Bioassays and Orion Diagnostica Oy, part of Finnish pharma company Orion Corporation, have inked an agreement for manufacturing of ultrasensitive estradiol, cortisol and testosterone radioimmunoassays, the pair said Monday.
Improved dialysis method for free thyroxin in serum compared with five commercial radioimmunoassays in nonthyroidal illness and subjects with abnormal concentrations of thyroxin-binding globulin.
Moreover, particularly for urgent clinical questions in critically ill patients, immunoassays are more widely and rapidly available than radioimmunoassays.
We performed radioimmunoassays for detecting brevetoxin using a sheep antisera prepared against a PbTx-2-fetuin conjugate (Garthwaite et al.
The use of nonisotope tags as replacements for radioimmunoassays has grown, but researchers cannot always obtain such assays for the substances they are testing.
The assay used in the study is estimated to be 50 to 100 times more sensitive than standard radioimmunoassays and can detect plasma estradiol levels as low as 0.
These included immune-linked tracers for insulin, studies that spawned today's radioimmunoassays for trace hormones and other molecules.
In radioimmunoassays, for example, the intra-assay coefficient of variation for precision may be 5% to 7%, whereas interassay reproducibility may be as high as 10% to 15%.
Radioimmunoassays and enzyme immunoassays are sensitive methods for quantifying many biologically active small molecules.
Small amounts of longer-lived isotopes used in radioimmunoassays -- such as cobalt-57 tritium, and carbon-14 -- enter the sewage system, she says, though they are "in such a diluted state that they pose no health risk.
Competitive protein binding assays were gradually replaced by radioimmunoassays.