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releasing factor

   Also found in: Medical, Encyclopedia, Wikipedia 0.03 sec.
re·leas·ing factor (r-lsng)
n.
Any of several hormones secreted by the hypothalamus that stimulate the anterior part of the pituitary gland to release certain hormones.
ThesaurusLegend:  Synonyms Related Words Antonyms
Noun1.releasing factor - a substance produced by the hypothalamus that is capable of accelerating the secretion of a given hormone by the anterior pituitary gland
factor - anything that contributes causally to a result; "a number of factors determined the outcome"
GHRF, growth hormone-releasing factor - a releasing factor that accelerates the secretion of growth hormone by the anterior pituitary body
2.releasing factor - any of several hormones produced in the hypothalamus and carried by a vein to the anterior pituitary gland where they stimulate the release of anterior pituitary hormones; each of these hormones causes the anterior pituitary to secrete a specific hormone
endocrine, hormone, internal secretion - the secretion of an endocrine gland that is transmitted by the blood to the tissue on which it has a specific effect


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Request for meeting submitted to FDA The company's lead compound, ThGRF, is an analogue of a natural hormone known as growth hormone releasing factor.
The Salk Institute for Biological Studies (La Jolla, CA) has patented a G-protein-coupled receptor proteins (CRF-R) characterized by having sufficient binding affinity for corticotropin releasing factor (CRF) such that concentrations of 10 nM of CRF occupy 50% of the binding sites of said receptor protein.
Neurogen Corporation (Branford, CT; 203-315-4615), a leading small molecule drug discovery and development company, and Aventis Pharma (Bridgewater, NJ; 908-231-4659), jointly announced an exclusive worldwide collaboration to develop new drugs for treatment of depression, anxiety, and other stress-related disorders based on Neurogen's innovative portfolio of pre-clinical corticotrophin releasing factor (CRF1) antagonist compounds.
 
 
 
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