We identified contigs with F1:A2:B20 plasmid replicons
in sequences from 20 of 24 isolates; the remaining isolates harbored contigs with F1:A6:B20, F1:A2:B20, F1:A2:B-, and F29:A-:B10 plasmid incompatibility groups.
Moreover, neither acquired resistance genes nor diversity of plasmids replicons
were found; however, variation in the in vitro intrinsic resistant pattern was detected, except the non-resistance to cefoxitin in all strains.
Characterization of extrachromosomol replicons
present in the extended host range Rhizobium.
Long stretches of short tandem repeats are present in the largest replicons
of the Archaea Haloferax mediterranei and Haloferax volcanii and could be involved in replicon
Plasmid incompatibility was determined for wild type as well as transformants by PCR based replicon
typing using 18 pairs of different basic replicon
primers, targetting FIA, FIB, FIC, HI1, HI2, I1-Ig, L/M, N, P, W, T, A/C, K, B/O, X, Y, F, and FIIA replicons
Genome replication does not require the presence of the viral structural proteins enabling the establishment of subgenomic replicons
that allow the analysis of genome replication in the absence of virion formation.
In in vitro studies, Daklinza has shown anti-viral activity across genotypes 1-6, with EC50 values from picomolar (pM) to low nanomolar (nM) against wild type replicons
This, coupled with our experience in the production of alphavirus replicons
aligns well with the fundamental needs of this research, " said TriLink President and CEO, Dr.
of the vectors pNZ124, pNZ2105, pNZ2103, pNZ7021, pNZ2122, and pNZ2123 are identical and came originally from the Lactococcus lactis plasmid pSH71.
In sections on genes and chromosomes, DNA replication and recombination, transcription and post-transcriptional mechanisms, and gene regulation, they consider such topics as the content of the genome, clusters and repeats, extrachomosomal replicons
, RNA splicing and processing, and phage strategies.
Cytopathogenic and noncytopathogenic RNA replicons
of Classical swine fever virus.
Sub-cellular material like genes, gene sequences, plasmids, replicons
and so on will come under the definition of a microorganism.