reporter gene


Also found in: Thesaurus, Medical, Legal, Encyclopedia, Wikipedia.
Related to reporter gene: Marker gene

reporter gene

n
(Genetics) a gene with an easily recognizable phenotype, used in analysing the regulation of gene structures
References in periodicals archive ?
Reagents & assay kits segment is further divided into reporter gene assays, second messenger assays, cell growth assays, cell death assays and other assays.
Offerings can also involve immunological diagnostic tools (IVD) for specific parameters, as well as functional cell-based reporter gene assays.
In our ongoing efforts to search for new STAT3 signaling pathway inhibitors from natural resources, we conducted a screening program targeting the inhibition of STAT3 signaling pathway and examined an extract library of Chinese herbs using a STAT3 luciferase reporter gene in HepG2 cells.
DIM stimulated ERbeta but not ERalpha activation of an estrogen response element upstream of the luciferase reporter gene.
One assay utilized a [beta]-lactamase reporter gene (the ARE-bla assay) and the other a luciferase reporter gene (the ARE-luc assay); the two assays differed in their ability to identify compounds that activate ARE through Nrf2-specific or nonspecific mechanisms.
Methods-To study flhD gene expression, the flhD promoter region was cloned in front of the open reading frame (ORF) of pUA66, contains gfpmut-2 as reporter gene.
This work describes the construction of metagenomic library from soil metagenome of high altitude region of Northwestern Himalaya using promoter less vector for entrapment of novel promoter sequences using GFP as reporter gene.
The term reporter gene is used to define a gene with a readily measurable phenotype that can be distinguished easily over a background of endogenous proteins (26).
The TRAC results were compared with a luciferase reporter gene assay.
In some of these studies, a team led by Brown used a reporter gene in conjunction with the assay to assess the amount of fungal growth in kernels.
Fusion of the reporter gene, GFP to each of the four Hc promoters has shown that all four strains have a functional M46 promoter.
The higher throughput of the six-channel instrument will allow small biotech and pharmaceutical companies a cost-effective approach to medium-throughput, Aequorin-based G protein-coupled receptor (GPCR) and Luciferase-based Reporter Gene Screening," said Andy Boorn, president of MDS Analytical Technologies.