GSI, in this model, serves to resensitise
cells to chemotherapy .
In some settings even when 3TC (or FTC) has been used in a failed first-line regimen (and therefore has probably selected for the M184V mutation which confers resistance to it) it is re-used in second line because of the capacity of the M184V mutation to partially resensitise
HIV to AZT, d4T and TDF in the presence of thymidine analogue mutations (TAMs) (and to partially resensitise
HIV to TDF in the presence of the K65R mutation).
His juxtaposition of forces was an index of community steeped in terror unless it began to re-sense or resensitise
a claustrophobic function of value .
EGFR and Akt signalling are often dysregulated in chemoresistant tumours, and their inhibition by gefitinib may resensitise
the cell to drug-induced apoptosis .